Angiography-Derived and Sensor-Wire Methods to Assess Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction

被引：30

作者：

Scarsini, Roberto ^{[1
,6
]}

Portolan, Leonardo ^{[1
]}

Della Mora, Francesco ^{[1
]}

Marin, Federico ^{[2
,3
,4
]}

Mainardi, Andrea ^{[1
]}

Ruzzarin, Alessandro ^{[1
]}

Levine, Molly B. ^{[5
]}

Banning, Adrian P. ^{[2
,3
,4
]}

Ribichini, Flavio ^{[1
]}

Garcia, Hector M. Garcia ^{[5
]}

De Maria, Giovanni Luigi ^{[2
,3
,4
,7
]}

机构：

[1] Univ Verona, Dept Med, Div Cardiol, Verona, Italy

[2] Oxford Univ Hosp NHS Trust, Oxford Heart Ctr, Oxford, England

[3] Natl Inst Hlth Res NIHR, Oxford Biomed Res Ctr, Oxford, England

[4] Univ Oxford, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England

[5] MedStar Washington Hosp Ctr, Intervent Cardiol, Washington, DC USA

[6] Verona Univ Hosp, Div Cardiol, Piazzale Stefani 1, I-37126 Verona, Italy

[7] Oxford Univ Hosp, Oxford Heart Ctr, Headley Way, Oxford OX3 9DU, England

来源：

JACC-CARDIOVASCULAR IMAGING | 2023年 / 16卷 / 07期

关键词：

acute coronary syndrome; acute myocardial infarction; angiography-derived index of microcirculatory resistance; coronary microvascular dysfunction; index of microcirculatory resistance; STEMI; ST-SEGMENT-ELEVATION; TIMI FRAME COUNT; BLOOD-FLOW MEASUREMENT; NO-REFLOW PHENOMENON; MICROCIRCULATORY RESISTANCE; PROGNOSTIC VALUE; INDEX; INTERVENTION; THERMODILUTION; REPERFUSION;

D O I：

10.1016/j.jcmg.2023.01.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

ST-segment elevation myocardial infarction (STEMI) treatment with primary percutaneous coronary intervention has dramatically impacted prognosis. However, despite satisfactory angiographic result, occurrence or persistence of coronary microvascular dysfunction after revascularization still affects long-term outcomes. The diagnostic and therapeutic value of understanding the status of coronary microcirculation is gaining attention in the cardiology community. However, current methods to assess microvascular function (namely, cardiac magnetic resonance and invasive wire-based coronary physiology) remain, at least in part, limited by technical and logistic aspects. On the other hand, angiography-based indices of microcirculatory resistance are emerging as valid and user-friendly tools with potential impact on prognostic stratification of patients with STEMI. This review provides an overview about conventional and novel methods to assess coronary microvascular dysfunction in patients with STEMI. The authors also provide a proposed procedural algorithm to facilitate optimal use of wire-based and angiography-based indices in the acute setting of STEMI. (c) 2023 by the American College of Cardiology Foundation.

引用

页码：965 / 981

页数：17

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