Metal-free transfer hydrogenation/cycloaddition cascade of activated quinolines and isoquinolines with tosyl azides

被引：3

作者：

Yadav, Suman ^{[1
]}

Kant, Ruchir ^{[2
]}

Kuram, Malleswara Rao ^{[1
,3
]}

机构：

[1] CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226031, India

[2] CSIR Cent Drug Res Inst, MSB Div, Lucknow 226031, India

[3] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 46期

关键词：

CYCLIC AMIDINES; BIOLOGICAL EVALUATION; DEAROMATIZATION; REDUCTION;

D O I：

10.1039/d3cc01430d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The difficulty in isolating cyclic enamines emanating from their intrinsic instability has impeded their exploration in cycloaddition reactions. Here, we achieved a metal-free domino reaction providing quinoline and isoquinoline-derived cyclic amidines by the cycloaddition of azides with in situ generated enamines via dearomatization.

引用

页码：7088 / 7091

页数：4

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