Serum vitamin D3 (25-OH vit D3) concentrations and hemogram changes in calves with enzootic pneumonia

被引:0
作者
Ertunc, Seviye [1 ]
Mecitoglu, Zafer [1 ]
Kasap, Sevim [1 ]
Senturk, Sezgin [1 ]
机构
[1] Uludağ Univ, Fac Vet Med, Dept Internal Med, Bursa, Turkiye
关键词
bovine; BRD; cattle; cholecalciferol; complete blood count; correlation analysis; BOVINE RESPIRATORY-DISEASE; OUTCOMES;
D O I
10.1111/vcp.13316
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Background: Enzootic pneumonia is an important disease complex associated with insufficient colostrum intake after birth, adverse environmental conditions, and stress. Vitamin D deficiency may be an important predisposing factor for this disease. Objective: This study aimed to investigate in calves with enzootic pneumonia. Methods: A total of 30 calves, aged 3-5 months, under the same care and feeding conditions were used. Groups were formed according to Clinical Respiratory Scoring as the group with mild/moderate enzootic pneumonia (n = 10), the group with severe enzootic pneumonia (n = 10), and the healthy control group (n = 10) without any disease. Blood samples were collected from the jugular vein of animals in all groups on Day 0; a complete blood count was performed, and serum vitamin D levels were measured using the Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) method. Results: Although no statistical differences were observed in total leukocyte, lymphocyte, eosinophil, basophil, hemoglobin, and hematocrit levels between groups, statistically significant differences in blood neutrophil, monocyte, and erythrocyte counts were found between the groups. Monocyte counts were statistically decreased in the mild/moderate group compared with the control group. Neutrophil counts were significantly higher in the mild/moderate and severe groups than in the control group. Erythrocyte counts were increased in the mild/moderate and severe groups compared with the control group. Vitamin D concentrations were statistically lower in the mild/moderate and severe groups than in the control group. However, no statistical differences in Vitamin D concentrations were observed between the mild/moderate and severe groups. There was a negative and significant correlation between erythrocyte counts and vitamin D concentrations (r = -0.64, P < .0001). While erythrocyte counts increased in the severe group compared with the mild/moderate group, vitamin D concentrations decreased. Also, a negative and significant correlation was observed between platelet counts and vitamin D concentrations (r = -0.74, P < .0001). Conclusions: The results of this study determined that serum vitamin D concentrations in calves with pneumonia were lower than those in healthy calves. Detailed studies on the etiologic and prognostic importance of low vitamin D levels in calves with enzootic pneumonia may provide valuable data for prevention and treatment.
引用
收藏
页码:74 / 79
页数:6
相关论文
共 31 条
[1]  
Al-Qudah KM, 2009, REV MED VET-TOULOUSE, V160, P231
[2]  
Altinel Acoglu E., 2019, TURKISH J PEDIAT DIS, V6, P442
[3]  
Arslan M., 2020, SAGLIK AKAD KASTAMON, V5, P65, DOI DOI 10.25279/SAK.423115
[4]   Vitamin D, innate immunity and upper respiratory tract infection [J].
Bartley, J. .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 2010, 124 (05) :465-469
[5]  
Bozukluhan Kadir, 2022, Saglik Bilimleri Veteriner Dergisi, Firat Universitesi, V36, P179
[6]   Vitamin D and Its Potential Benefit for the COVID-19 Pandemic [J].
Charoenngam, Nipith ;
Shirvani, Arash ;
Holick, Michael F. .
ENDOCRINE PRACTICE, 2021, 27 (05) :484-493
[7]   25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2 [J].
D'Avolio, Antonio ;
Avataneo, Valeria ;
Manca, Alessandra ;
Cusato, Jessica ;
De Nicolo, Amedeo ;
Lucchini, Renzo ;
Keller, Franco ;
Cantu, Marco .
NUTRIENTS, 2020, 12 (05)
[8]  
Erkus E, 2018, JCPSP-J COLL PHYSICI, V28, P779, DOI 3021
[9]   Can erythrocytes behavior in microcirculation help the understanding the physiopathology and improve prevention and treatment for covid-19? [J].
Farber, Paulo Luiz .
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2021, 78 (01) :41-47
[10]   Low serum vitamin D concentrations in Spring-born dairy calves are associated with elevated peripheral leukocytes [J].
Flores-Villalva, Susana ;
O'Brien, Megan B. ;
Reid, Cian ;
Lacey, Sean ;
Gordon, Stephen, V ;
Nelson, Corwin ;
Meade, Kieran G. .
SCIENTIFIC REPORTS, 2021, 11 (01)