Children's Oncology Group's 2023 blueprint for research: Pediatric liver tumors

被引：4

作者：

O'Neill, Allison F. ^{[1
,2
]}

Meyers, Rebecka L. ^{[3
]}

Katzenstein, Howard M. ^{[4
]}

Geller, James, I ^{[5
]}

Tiao, Greg M. ^{[6
]}

Lopez-Terrada, Dolores ^{[7
]}

Malogolowkin, Marcio ^{[8
]}

机构：

[1] Dana Farber Canc Inst, Dept Pediat Oncol, Boston, MA 02215 USA

[2] Harvard Med Sch, Boston, MA 02115 USA

[3] Univ Utah, Div Pediat Surg, Salt Lake City, UT USA

[4] Nemours Childrens Hosp, Wilmington, DE USA

[5] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Div Oncol, Cincinnati, OH USA

[6] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Div Surg, Cincinnati, OH USA

[7] Texas Childrens Hosp & Canc Ctr, Baylor Coll Med, Dept Pathol & Immunol, Houston, TX USA

[8] Univ Calif Davis, Comprehens Canc Ctr, Pediat Oncol, Sacramento, CA USA

来源：

PEDIATRIC BLOOD & CANCER | 2023年 / 70卷

关键词：

hepatoblastoma; hepatocellular; international; liver; pediatric; PRETREATMENT PROGNOSTIC-FACTORS; HIGH-RISK HEPATOBLASTOMA; INDUCED HEARING-LOSS; JAPANESE-STUDY-GROUP; INTERNATIONAL-SOCIETY; HEPATOCELLULAR-CARCINOMA; CHILDHOOD HEPATOBLASTOMA; SODIUM THIOSULFATE; GENOMIC ANALYSIS; CANCER GROUP;

D O I：

10.1002/pbc.30576

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Liver tumors account for approximately 1%-2% of all pediatric malignancies, with the two most common tumors being hepatoblastoma (HB) and hepatocellular carcinoma (HCC). Previous Children's Oncology Group studies have meaningfully contributed to the current understanding of disease pathophysiology and treatment, laying groundwork for the ongoing prospective international study of both HB and HCC. Future work is focused on elucidating the biologic underpinnings of disease to support an evolution in risk categorization, advancements in the multidimensional care required to treat these patients, and the discovery of novel therapies.

引用

页数：12

共 87 条

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