Acute Kidney Injury in Patients Admitted to the Intensive Care Unit: A Case Report

被引:2
作者
Mohamed, Ayman [1 ]
Peniston, Michael [2 ]
Mahmood, Rabia [1 ]
机构
[1] Ascens St John Hosp, Internal Med, Detroit, MI 48236 USA
[2] Ascens St John Hosp, Internal Med, Michigan, ND USA
关键词
ercp; critical care; acute kidney injury; cholemic nephropathy; medical intensive care unit (micu); NEPHROPATHY;
D O I
10.7759/cureus.40380
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains the most prevalent. Cholemic nephropathy (CN) is a rare cause of AKI. Patients with CN usually present with elevated total bilirubin levels of greater than 20 mg/dl. However, CN has been reported in patients with total bilirubin levels of less than 20 mg/dL. These patients were found to have chronic elevations of bilirubin due to chronic liver disease rather than an acute rise in bilirubin levels. In this case series, we present two cases of patients with chronic liver disease who were admitted to the intensive care unit and were found to have AKI with elevated total bilirubin levels over 15 mg/dl.
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相关论文
共 7 条
[1]   Cholemic Nephropathy Causes Acute Kidney Injury and Is Accompanied by Loss of Aquaporin 2 in Collecting Ducts [J].
Braesen, Jan Hinrich ;
Mederacke, Young-Seon ;
Schmitz, Jessica ;
Diahovets, Kateryna ;
Khalifa, Abedalrazag ;
Hartleben, Bjoern ;
Person, Fermin ;
Wiech, Thorsten ;
Steenbergen, Eric ;
Grosshennig, Anika ;
Manns, Michael P. ;
Schmitt, Roland ;
Mederacke, Ingmar .
HEPATOLOGY, 2019, 69 (05) :2107-2119
[2]  
Eswarappa M, 2014, Indian J Nephrol, V24, P280, DOI 10.4103/0971-4065.132991
[3]  
Foshat M, 2017, AM J CLIN PATHOL, V147, P525, DOI [10.1093/ajcp/aqx030, 10.1093/AJCP/AQX030]
[4]   Global epidemiology and outcomes of acute kidney injury [J].
Hoste, Eric A. J. ;
Kellum, John A. ;
Selby, Nicholas M. ;
Zarbock, Alexander ;
Palevsky, Paul M. ;
Bagshaw, Sean M. ;
Goldstein, Stuart L. ;
Cerda, Jorge ;
Chawla, Lakhmir S. .
NATURE REVIEWS NEPHROLOGY, 2018, 14 (10) :607-625
[5]   Incidence, risk factors, and prognosis of acute kidney injury in hospitalized patients with acute cholangitis [J].
Lee, Tae Won ;
Bae, Wooram ;
Kim, Seongmin ;
Choi, Jungyoon ;
Bae, Eunjin ;
Jang, Ha Nee ;
Chang, Se-Ho ;
Park, Dong Jun .
PLOS ONE, 2022, 17 (04)
[6]   Bile cast nephropathy: A case report and review of the literature [J].
Patel, Jaymon ;
Walayat, Saqib ;
Kalva, Nikhil ;
Palmer-Hill, Sidney ;
Dhillon, Sonu .
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (27) :6328-6334
[7]   Cholemic Nephropathy as Cause of Acute and Chronic Kidney Disease. Update on an Under-Diagnosed Disease [J].
Tinti, Francesca ;
Umbro, Ilaria ;
D'Alessandro, Mariadomenica ;
Lai, Silvia ;
Merli, Manuela ;
Noce, Annalisa ;
Di Daniele, Nicola ;
Mazzaferro, Sandro ;
Mitterhofer, Anna Paola .
LIFE-BASEL, 2021, 11 (11)