The importance of sex and gender in basic and clinical research

被引:7
作者
Ahmed, Sofia B. [1 ,2 ,3 ,4 ]
机构
[1] Univ Calgary, Cumming Sch Med, Calgary, AB, Canada
[2] Libin Cardiovasc Inst, Calgary, AB, Canada
[3] OBrien Inst Publ Hlth, Calgary, AB, Canada
[4] Alberta Kidney Dis Network, Calgary, AB, Canada
关键词
D O I
10.1038/s41581-023-00716-x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The importance of incorporating factors related to sex and gender in all aspects of research is increasingly recognized. Kidney disease pathophysiology, presentation, response to therapy and outcomes differ by sex and gender, but these factors are often not considered in basic and clinical studies. It is time for nephrology to catch up.
引用
收藏
页码:2 / 3
页数:2
相关论文
共 10 条
[1]   Female sex-specific considerations to improve rigor and reproducibility in cardiovascular research [J].
Chang, Danica H. ;
Dumanski, Sandra M. ;
Ahmed, Sofia B. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2023, 324 (03) :H279-H287
[2]   Sex and Gender in Randomized Controlled Trials of Adults Receiving Maintenance Dialysis: A Meta-epidemiologic Study [J].
Collister, David ;
Pyne, Lonnie ;
Bhasin, Arrti A. ;
Ahmed, Sotla B. ;
Smyth, Brendan ;
Herrington, William ;
Jardine, Meg ;
Walsh, Michael .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2023, 81 (05) :575-582.e1
[3]   Sex differences in kidney gene expression during the life cycle of F344 rats [J].
Kwekel, Joshua C. ;
Desai, Varsha G. ;
Moland, Carrie L. ;
Vijay, Vikrant ;
Fuscoe, James C. .
BIOLOGY OF SEX DIFFERENCES, 2013, 4
[4]   Measuring sex, gender, and sexual orientation: one step to health equity [J].
Logie, Carmen H. ;
van der Merwe, L. Leigh Ann ;
Scheim, Ayden .
LANCET, 2022, 400 (10354) :715-717
[5]   Sex and the kidneys: current understanding and research opportunities [J].
Merz, C. Noel Bairey ;
Dember, Laura M. ;
Ingelfinger, Julie R. ;
Vinson, Amanda ;
Neugarten, Joel ;
Sandberg, Kathryn L. ;
Sullivan, Jennifer C. ;
Maric-Bilkan, Christine ;
Rankin, Tracy L. ;
Kimmel, Paul L. ;
Star, Robert A. .
NATURE REVIEWS NEPHROLOGY, 2019, 15 (12) :776-783
[6]   Improving the inclusion of transgender and nonbinary individuals in the planning, completion, and mobilization of cardiovascular research [J].
Rytz, Chantal L. ;
Beach, Lauren B. ;
Saad, Nathalie ;
Dumanski, Sandra M. ;
Collister, David ;
Newbert, Amelia M. ;
Peace, Lindsay ;
Lett, Elle ;
Greene, Dina ;
Connelly, Paul ;
Veale, Jaimie ;
Morillo, Cris ;
Ahmed, Sofia B. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2023, 324 (03) :H366-H372
[7]   Factors affecting sex-related reporting in medical research: a cross-disciplinary bibliometric analysis [J].
Sugimoto, Cassidy R. ;
Ahn, Yong-Yeol ;
Smith, Elise ;
Macaluso, Benoit ;
Lariviere, Vincent .
LANCET, 2019, 393 (10171) :550-559
[8]   Sex-Specific Considerations in Guidelines Generation and Application [J].
Tannenbaum, Cara ;
Norris, Colleen M. ;
McMurtry, M. Sean .
CANADIAN JOURNAL OF CARDIOLOGY, 2019, 35 (05) :598-605
[9]  
United States General Accounting Office, 2001, DRUG SAF MOST DRUGS
[10]   Underrepresentation of Women in Recent Landmark Kidney Trials: The Gender Gap Prevails [J].
Vinson, Amanda J. ;
Collister, David ;
Ahmed, Sofia ;
Tennankore, Karthik .
KIDNEY INTERNATIONAL REPORTS, 2022, 7 (11) :2526-2529