The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial

被引：0
|
作者：
Hossam, Mariam Ahmed [1 ]
El Baz, Alaa Abdelsalam [1 ]
Kwak, Sang Won [2 ]
Kim, Hyeon-Cheol [2 ,3 ]
Abielhassan, Mohamed Mohsen [1 ,4 ]
机构：
[1] Cairo Univ, Fac Dent, Dept Endodont, Giza, Egypt
[2] Pusan Natl Univ, Dent Res Inst, Dent & Life Sci Inst, Sch Dent,Det Conservat Dent, Yangsan, South Korea
[3] Pusan Natl Univ, Sch Dent, Dept Conservat Dent, Geumo ro 20, Yangsan 50612, Gyeongnam, South Korea
[4] Cairo Univ, Fac Dent, Dept Endodont, 415 Zayed 2000 residential Cpd, Shiekh Zayed City, Giza, Egypt
来源：
AUSTRALIAN ENDODONTIC JOURNAL | 2024年 / 50卷 / 02期
关键词：
ibuprofen; irreversible pulpitis; mandibular molars; postoperative pain; premedication; sustained release; ALVEOLAR NERVE BLOCK; IRREVERSIBLE PULPITIS; PREOPERATIVE IBUPROFEN; ANESTHETIC EFFICACY; MANDIBULAR MOLARS; DOUBLE-BLIND; SUCCESS; DEXAMETHASONE; ARTICAINE; SINGLE;
D O I：
10.1111/aej.12839
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single-visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.
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页码：227 / 236
页数：10
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