The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial

被引:0
|
作者
Hossam, Mariam Ahmed [1 ]
El Baz, Alaa Abdelsalam [1 ]
Kwak, Sang Won [2 ]
Kim, Hyeon-Cheol [2 ,3 ]
Abielhassan, Mohamed Mohsen [1 ,4 ]
机构
[1] Cairo Univ, Fac Dent, Dept Endodont, Giza, Egypt
[2] Pusan Natl Univ, Dent Res Inst, Dent & Life Sci Inst, Sch Dent,Det Conservat Dent, Yangsan, South Korea
[3] Pusan Natl Univ, Sch Dent, Dept Conservat Dent, Geumo ro 20, Yangsan 50612, Gyeongnam, South Korea
[4] Cairo Univ, Fac Dent, Dept Endodont, 415 Zayed 2000 residential Cpd, Shiekh Zayed City, Giza, Egypt
关键词
ibuprofen; irreversible pulpitis; mandibular molars; postoperative pain; premedication; sustained release; ALVEOLAR NERVE BLOCK; IRREVERSIBLE PULPITIS; PREOPERATIVE IBUPROFEN; ANESTHETIC EFFICACY; MANDIBULAR MOLARS; DOUBLE-BLIND; SUCCESS; DEXAMETHASONE; ARTICAINE; SINGLE;
D O I
10.1111/aej.12839
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single-visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.
引用
收藏
页码:227 / 236
页数:10
相关论文
共 50 条
  • [21] The effect of food on the bioavailability of ibuprofen and flurbiprofen from sustained release formulations
    Pargal, A
    Kelkar, MG
    Nayak, PJ
    BIOPHARMACEUTICS & DRUG DISPOSITION, 1996, 17 (06) : 511 - 519
  • [22] The effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single-centre randomized controlled trial
    Elkhadem, A.
    Ezzat, K.
    Ramadan, M.
    AbdelGhaffar, S.
    Khamis, D.
    Hassan, A.
    Abdel-Mawgoud, A.
    Mamdouh, A.
    AbouZeid, M.
    Amin, S.
    INTERNATIONAL ENDODONTIC JOURNAL, 2018, 51 : E189 - E196
  • [23] Single dose oral ibuprofen for acute postoperative pain in adults
    Derry, C.
    Derry, S.
    Moore, R. A.
    McQuay, H. J.
    COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2009, (03):
  • [24] Synergistic Effect of Intravenous Ibuprofen and Hydromorphone for Postoperative Pain: Prospective Randomized Controlled Trial
    Oh, Eun Jung
    Ahn, Hyun Joo
    Sim, Woo Seog
    Lee, Jin Young
    PAIN PHYSICIAN, 2016, 19 (06) : 341 - 348
  • [25] Effect of Diclofenac Potassium Premedication on Postendodontic Pain in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Randomized Placebo-Controlled Double-Blind Trial
    Al-Rawhani, Amatallah Hussein
    Gawdat, Shaimaa Ismail
    Amin, Suzan Abdul Wanees
    JOURNAL OF ENDODONTICS, 2020, 46 (08) : 1023 - 1031
  • [26] Effect of Nonsteroidal Anti-inflammatory Drug as an Oral Premedication on the Anesthetic Success of Inferior Alveolar Nerve Block in Treatment of Irreversible Pulpitis: A Systematic Review with Meta-analysis and Trial Sequential Analysis
    Nagendrababu, Venkateshbabu
    Pulikkotil, Shaju Jacob
    Veettil, Sajesh K.
    Teerawattanapong, Nattawat
    Setzet, Frank C.
    JOURNAL OF ENDODONTICS, 2018, 44 (06) : 914 - 922
  • [27] The Impact of Baseline Pain Intensity on the Analgesic Efficacy of Ibuprofen/Caffeine in Patients with Acute Postoperative Dental Pain: Post Hoc Subgroup Analysis of a Randomised Controlled Trial
    Foerderreuther, Stefanie
    Lampert, Anette
    Hitier, Simon
    Lange, Robert
    Weiser, Thomas
    ADVANCES IN THERAPY, 2020, 37 (06) : 2976 - 2987
  • [28] The Impact of Baseline Pain Intensity on the Analgesic Efficacy of Ibuprofen/Caffeine in Patients with Acute Postoperative Dental Pain: Post Hoc Subgroup Analysis of a Randomised Controlled Trial
    Stefanie Förderreuther
    Anette Lampert
    Simon Hitier
    Robert Lange
    Thomas Weiser
    Advances in Therapy, 2020, 37 : 2976 - 2987
  • [29] A Randomized Clinical Trial Comparing 2 Ibuprofen Formulations in Patients with Acute Odontogenic Pain
    Taggar, Tanjit
    Wu, Di
    Khan, Asma A.
    JOURNAL OF ENDODONTICS, 2017, 43 (05) : 674 - 678
  • [30] Effect of long acting local anesthetic on postoperative pain in teeth with irreversible pulpitis: Randomized clinical trial
    Al-Kahtani, Ahmed
    SAUDI PHARMACEUTICAL JOURNAL, 2014, 22 (01) : 39 - 42