The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial

被引:0
作者
Hossam, Mariam Ahmed [1 ]
El Baz, Alaa Abdelsalam [1 ]
Kwak, Sang Won [2 ]
Kim, Hyeon-Cheol [2 ,3 ]
Abielhassan, Mohamed Mohsen [1 ,4 ]
机构
[1] Cairo Univ, Fac Dent, Dept Endodont, Giza, Egypt
[2] Pusan Natl Univ, Dent Res Inst, Dent & Life Sci Inst, Sch Dent,Det Conservat Dent, Yangsan, South Korea
[3] Pusan Natl Univ, Sch Dent, Dept Conservat Dent, Geumo ro 20, Yangsan 50612, Gyeongnam, South Korea
[4] Cairo Univ, Fac Dent, Dept Endodont, 415 Zayed 2000 residential Cpd, Shiekh Zayed City, Giza, Egypt
关键词
ibuprofen; irreversible pulpitis; mandibular molars; postoperative pain; premedication; sustained release; ALVEOLAR NERVE BLOCK; IRREVERSIBLE PULPITIS; PREOPERATIVE IBUPROFEN; ANESTHETIC EFFICACY; MANDIBULAR MOLARS; DOUBLE-BLIND; SUCCESS; DEXAMETHASONE; ARTICAINE; SINGLE;
D O I
10.1111/aej.12839
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single-visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.
引用
收藏
页码:227 / 236
页数:10
相关论文
共 31 条
[1]  
Bailey Edmund, 2018, Prim Dent J, V7, P57
[2]   Ibuprofen and diclofenac sodium in the treatment of osteoarthritis: A comparative trial of two once-daily sustained-release NSAID formulations [J].
Baumgartner, H ;
Schwarz, HA ;
Blum, W ;
Bruhin, A ;
Gallachi, G ;
Goldinger, G ;
Saxer, M ;
Trost, H .
CURRENT MEDICAL RESEARCH AND OPINION, 1996, 13 (08) :435-444
[3]  
Bidar M, 2017, BULL TOKYO DENT COLL, V58, P231, DOI 10.2209/tdcpublication.2016-0050
[4]   Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies [J].
Christensen, Steven ;
Paluch, Ed ;
Jayawardena, Shyamalie ;
Daniels, Stephen ;
Meeves, Suzanne .
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2017, 6 (03) :302-312
[5]   Effects of Ibuprofen Compared to Other Premedication Drugs on the Risk and Intensity of Postendodontic Pain: A Systematic Review [J].
De Geus, Juliana L. ;
Wambier, Leticia M. ;
Boing, Thaynara F. ;
Loguercio, Alessandro D. ;
Reis, Alessandra .
EUROPEAN ENDODONTIC JOURNAL, 2018, 3 (03) :123-133
[6]   Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis [J].
Elnaghy, Amr M. ;
Elshazli, Alaa H. ;
Badr, Amany E. ;
Elsaka, Shaymaa E. .
AUSTRALIAN ENDODONTIC JOURNAL, 2023, 49 (01) :165-173
[7]   Effect of XP-endo Shaper versus conventional rotary files on postoperative pain and bacterial reduction in oval canals with necrotic pulps: a randomized clinical study [J].
Emara, R. S. ;
Gawdat, S. I. ;
El-Far, H. M. M. .
INTERNATIONAL ENDODONTIC JOURNAL, 2021, 54 (07) :1026-1036
[8]   The effectiveness of articaine in mandibular facial infiltrations [J].
Flanagan, Dennis F. .
LOCAL AND REGIONAL ANESTHESIA, 2016, 9 :1-6
[9]  
Gupta Alpa, 2021, J Dent Anesth Pain Med, V21, P283, DOI 10.17245/jdapm.2021.21.4.283
[10]  
Jorge-Araújo Adrian Camargo Amaral, 2018, Braz. Dent. J., V29, P254, DOI 10.1590/0103-6440201801786