Leveraging circulating microbial DNA for early cancer detection

被引：5

作者：

Kataria, Radhika ^{[1
,2
,3
]}

Shoaie, Saeed ^{[2
,4
]}

Grigoriadis, Anita ^{[1
,3
,5
]}

Wan, Jonathan C. M. ^{[1
,6
]}

机构：

[1] Kings Coll London, Sch Canc & Pharmaceut Sci, Fac Life Sci & Med, Canc Bioinformat, London, England

[2] Kings Coll London, Fac Dent Oral & Craniofacial Sci, Ctr Host Microbiome Interact, London, England

[3] Kings Coll London, Fac Life Sci & Med, Sch Canc & Pharmaceut Sci, London, England

[4] KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden

[5] Kings Coll London, Fac Life Sci & Med, Sch Canc & Pharmaceut Sci, Breast Canc Now Res Unit, London, England

[6] Univ Coll London Hosp, Euston Rd, London, England

来源：

TRENDS IN CANCER | 2023年 / 9卷 / 11期

基金：

英国生物技术与生命科学研究理事会; 英国医学研究理事会; 英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/j.trecan.2023.08.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.

引用

页码：879 / 882

页数：4

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