NIR-II Aggregation-Induced Emission for PDT-PTT Dual-Mode Synergistic Therapy

被引:4
作者
Tang, Hui [1 ]
Li, Hairong [1 ]
Liu, Xiaochun [1 ]
Zhang, Yahui [1 ]
Wang, Zhouyu [1 ]
Yu, Xiaoqi [1 ]
机构
[1] Xihua Univ, Sch Sci, Dept Chem, Chengdu 610039, Peoples R China
基金
中国国家自然科学基金;
关键词
aggregation-induced emission; the second near-infrared emission; photodynamic-photothermal dual-mode synergistic therapy; DESIGN; DYES;
D O I
10.7536/PC221230
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Due to the excellent optical properties, good biocompatibility, high reactive oxygen species yield and excellent photothermal conversion ability, aggregation-induced emission ( AIE) materials show great potential applications in the fields of photodynamic and photothermal therapy. However, traditional fluorescent materials need light with short wavelength for emission, which has the problem of poor tissue penetration, and further restricts the clinical application. To overcome the problem, AIE materials with emission in the range of second near-infrared (NIR-II) emission are employed, which promotes the feasibility of the clinical application. This review summarizes the application of NIR-II AIEgens with donor-pi-acceptor ( D-pi-A ) and donor-acceptor donor (D-A-D) structure in photodynamic-photothermal dual-mode synergistic therapy.
引用
收藏
页码:1399 / 1414
页数:16
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