Inhibiting C5a/C5aR to treat ANCA-associated vasculitides

被引：2
作者：
Terrier, Benjamin [1 ]
Karras, Alexandre [2 ]
机构：
[1] Univ Paris Cite, Hop Cochin, Assistance Publ Hop Paris, Natl Referral Ctr Rare Autoimmune & Syst Dis,Dept, 27 Rue Faubourg St Jacques, F-75679 Paris 14, France
[2] Univ Paris Cite, Hop Europeen Georges Pompidou, Assistance Publ Hop Paris, Dept Nephrol, Paris, France
来源：
JOINT BONE SPINE | 2023年 / 90卷 / 02期
关键词：
Vasculitis; ANCA; C5a; C5aR; Avacopan; RITUXIMAB; GLUCOCORTICOIDS;
D O I：
10.1016/j.jbspin.2022.105472
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：2
相关论文
共 10 条
  • [1] Long-term patient survival in ANCA-associated vasculitis
    Flossmann, Oliver
    Berden, Annelies
    de Groot, Kirsten
    Hagen, Chris
    Harper, Lorraine
    Heijl, Caroline
    Hoglund, Peter
    Jayne, David
    Luqmani, Raashid
    Mahr, Alfred
    Mukhtyar, Chetan
    Pusey, Charles
    Rasmussen, Niels
    Stegeman, Coen
    Walsh, Michael
    Westman, Kerstin
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2011, 70 (03) : 488 - 494
  • [2] Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis A Randomized Clinical Trial
    Furuta, Shunsuke
    Nakagomi, Daiki
    Kobayashi, Yoshihisa
    Hiraguri, Masaki
    Sugiyama, Takao
    Amano, Koichi
    Umibe, Takeshi
    Kono, Hajime
    Kurasawa, Kazuhiro
    Kita, Yasuhiko
    Matsumura, Ryutaro
    Kaneko, Yuko
    Ninagawa, Keita
    Hiromura, Keiju
    Kagami, Shin-ichiro
    Inaba, Yosuke
    Hanaoka, Hideki
    Ikeda, Kei
    Nakajima, Hiroshi
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 325 (21): : 2178 - 2187
  • [3] Avacopan for the Treatment of ANCA-Associated Vasculitis
    Jayne, David R. W.
    Merkel, Peter A.
    Schall, Thomas J.
    Bekker, Pirow
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (07) : 599 - 609
  • [4] Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis
    Jayne, David R. W.
    Bruchfeld, Annette N.
    Harper, Lorraine
    Schaier, Matthias
    Venning, Michael C.
    Hamilton, Patrick
    Burst, Volker
    Grundmann, Franziska
    Jadoul, Michel
    Szombati, Istvan
    Tesar, Vladimir
    Segelmark, Marten
    Potarca, Antonia
    Schall, Thomas J.
    Bekker, Pirow
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017, 28 (09): : 2756 - 2767
  • [5] Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
    Merkel, Peter A.
    Niles, John
    Jimenez, Richard
    Spiera, Robert F.
    Rovin, Brad H.
    Bomback, Andrew
    Pagnoux, Christian
    Potarca, Antonia
    Schall, Thomas J.
    Bekker, Pirow
    [J]. ACR OPEN RHEUMATOLOGY, 2020, 2 (11) : 662 - 671
  • [6] Treatment of Systemic Necrotizing Vasculitides in Patients Aged Sixty-Five Years or Older
    Pagnoux, Christian
    Quemeneur, Thomas
    Ninet, Jacques
    Diot, Elisabeth
    Kyndt, Xavier
    de Wazieres, Benoit
    Reny, Jean-Luc
    Puechal, Xavier
    le Berruyer, Pierre-Yves
    Lidove, Olivier
    Vanhille, Philippe
    Godmer, Pascal
    Fain, Olivier
    Blockmans, Daniel
    Bienvenu, Boris
    Rollot, Florence
    Ait el Ghaz-Poignant, Severine
    Mahr, Alfred
    Cohen, Pascal
    Mouthon, Luc
    Perrodeau, Elodie
    Ravaud, Philippe
    Guillevin, Loic
    [J]. ARTHRITIS & RHEUMATOLOGY, 2015, 67 (04) : 1117 - 1127
  • [7] Pugnet G, 2016, CLIN EXP RHEUMATOL, V34, pS54
  • [8] Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis.
    Stone, John H.
    Merkel, Peter A.
    Spiera, Robert
    Seo, Philip
    Langford, Carol A.
    Hoffman, Gary S.
    Kallenberg, Cees G. M.
    Clair, E. William St.
    Turkiewicz, Anthony
    Tchao, Nadia K.
    Webber, Lisa
    Ding, Linna
    Sejismundo, Lourdes P.
    Mieras, Kathleen
    Weitzenkamp, David
    Ikle, David
    Seyfert-Margolis, Vicki
    Mueller, Mark
    Brunetta, Paul
    Allen, Nancy B.
    Fervenza, Fernando C.
    Geetha, Duvuru
    Keogh, Karina A.
    Kissin, Eugene Y.
    Monach, Paul A.
    Peikert, Tobias
    Stegeman, Coen
    Ytterberg, Steven R.
    Specks, Ulrich
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (03) : 221 - 232
  • [9] Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis
    Walsh, Michael
    Merkel, Peter A.
    Peh, Chen-Au
    Szpirt, Wladimir M.
    Puechal, Xavier
    Fujimoto, Shouichi
    Hawley, Carmel M.
    Khalidi, Nader
    Flossmann, Oliver
    Wald, Ron
    Girard, Louis P.
    Levin, Adeera
    Gregorini, Gina
    Harper, Lorraine
    Clark, William F.
    Pagnoux, Christian
    Specks, Ulrich
    Smyth, Lucy
    Tesar, Vladimir
    Ito-Ihara, Toshiko
    de Zoysa, Janak Rashme
    Szczeklik, Wojciech
    Flores-Suarez, Luis Felipe
    Carette, Simon
    Guillevin, Loic
    Pusey, Charles D.
    Casian, Alina L.
    Brezina, Biljana
    Mazzetti, Andrea
    McAlear, Carol A.
    Broadhurst, Elizabeth
    Reidlinger, Donna
    Mehta, Samir
    Ives, Natalie
    Jayne, David R. W.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (07) : 622 - 631
  • [10] C5a Receptor (CD88) Blockade Protects against MPO-ANCA GN
    Xiao, Hong
    Dairaghi, Daniel J.
    Powers, Jay P.
    Ertl, Linda S.
    Baumgart, Trageen
    Wang, Yu
    Seitz, Lisa C.
    Penfold, Mark E. T.
    Gan, Lin
    Hu, Peiqi
    Lu, Bao
    Gerard, Norma P.
    Gerard, Craig
    Schall, Thomas J.
    Jaen, Juan C.
    Falk, Ronald J.
    Jennette, J. Charles
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 25 (02): : 225 - 231
1