Case Report: Telitacicept in severe myasthenia gravis: a case study with multiple autoantibodies

被引：4
|
作者：
Guo, Qian [1 ]
Huang, Yusen [1 ]
Wang, Fangruyue [2 ]
Fang, Le [1 ]
机构：
[1] Jilin Univ, Dept Neurol, China Japan Union Hosp, Changchun, Peoples R China
[2] Jilin Univ, Bethune Hosp 3, Changchun, Peoples R China
来源：
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
关键词：
myasthenia gravis; Titin-Ab; RyR-Ab; AChR-Ab; Telitacicept; case report; QUALITY-OF-LIFE; TITIN; ANTIBODIES; THYMOMA;
D O I：
10.3389/fimmu.2023.1270011
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Multi-antibody-positive myasthenia gravis (MG) presentations are relatively rare, often found in older patients, and generally predict a poor prognosis. We report a case of a female patient with generalized MG, testing positive for Titin antibodies (Titin-Ab), ryanodine receptor antibodies (RyR-Ab), and acetylcholine receptor antibodies (AChR-Ab), and resistant to acetylcholinesterase inhibitors. Following unsuccessful traditional therapies, she received Telitacicept, leading to significant improvements. This case underscores Telitacicept's potential efficacy for similar patients and offers insights into the clinical characteristics of multi-antibody MG.
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页数：5
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