[1] Univ Leicester, Leicester Gen Hosp, Diabet Res Ctr, Leicester, England
[2] Univ Eastern Finland, Inst Clin Med, Dept Med, Kuopio, Finland
[3] Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland
[4] Wellbeing Serv Cty Cent Finland, Dept Med, Jyvaskyla, Finland
[5] Univ Leicester, Leicester Gen Hosp, Diabet Res Ctr, Gwendolen Rd, Leicester LE5 4WP, England