Today's Kaposi sarcoma is not the same as it was 40 years ago, or is it?

被引：10

作者：

Damania, Blossom ^{[1
,2
]}

Dittmer, Dirk P. ^{[1
,2
]}

机构：

[1] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, Sch Med, Dept Microbiol & Immunol, Chapel Hill, NC USA

[2] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, Sch Med, Dept Microbiol & Immunol, 450 West Dr CB 7295,Rm 12-048, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF MEDICAL VIROLOGY | 2023年 / 95卷 / 05期

关键词：

herpesvirus; Kaposi sarcoma; KSHV; PRIMARY EFFUSION LYMPHOMA; PEGYLATED-LIPOSOMAL DOXORUBICIN; MULTICENTRIC CASTLEMAN DISEASE; INFLAMMATORY CYTOKINE SYNDROME; BLOOD MONONUCLEAR-CELLS; HIV-NEGATIVE MEN; DNA-SEQUENCES; ENDOTHELIAL-CELLS; GENE-EXPRESSION; C-MYC;

D O I：

10.1002/jmv.28773

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This review will provide an overview of the notion that Kaposi sarcoma (KS) is a disease that manifests under diverse and divergent circumstances. We begin with a historical introduction of KS and KS-associated herpesvirus (KSHV), highlight the diversity of clinical presentations of KS, summarize what we know about the cell of origin for this tumor, explore KSHV viral load as a potential biomarker for acute KSHV infections and KS-associated complications, and discuss immune modulators that impact KSHV infection, KSHV persistence, and KS disease.

引用

页数：13

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