Today's Kaposi sarcoma is not the same as it was 40 years ago, or is it?

被引：10
|
作者：
Damania, Blossom [1 ,2 ]
Dittmer, Dirk P. [1 ,2 ]
机构：
[1] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, Sch Med, Dept Microbiol & Immunol, Chapel Hill, NC USA
[2] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, Sch Med, Dept Microbiol & Immunol, 450 West Dr CB 7295,Rm 12-048, Chapel Hill, NC 27599 USA
来源：
JOURNAL OF MEDICAL VIROLOGY | 2023年 / 95卷 / 05期
关键词：
herpesvirus; Kaposi sarcoma; KSHV; PRIMARY EFFUSION LYMPHOMA; PEGYLATED-LIPOSOMAL DOXORUBICIN; MULTICENTRIC CASTLEMAN DISEASE; INFLAMMATORY CYTOKINE SYNDROME; BLOOD MONONUCLEAR-CELLS; HIV-NEGATIVE MEN; DNA-SEQUENCES; ENDOTHELIAL-CELLS; GENE-EXPRESSION; C-MYC;
D O I：
10.1002/jmv.28773
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This review will provide an overview of the notion that Kaposi sarcoma (KS) is a disease that manifests under diverse and divergent circumstances. We begin with a historical introduction of KS and KS-associated herpesvirus (KSHV), highlight the diversity of clinical presentations of KS, summarize what we know about the cell of origin for this tumor, explore KSHV viral load as a potential biomarker for acute KSHV infections and KS-associated complications, and discuss immune modulators that impact KSHV infection, KSHV persistence, and KS disease.
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收藏
页数：13
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