Pulmonary Veno-occlusive Disease that Developed Following Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia

被引：1
作者：
Takeda, Kenichiro [1 ]
Naito, Akira [1 ]
Sugiura, Toshihiko [1 ]
Ishige, Masaki [1 ]
Shikano, Kohei [1 ]
Abe, Mitsuhiro [1 ]
Kasai, Hajime [1 ]
Miyakuni, Shota [1 ]
Yamashita, Shu [2 ]
Shigeta, Ayako [1 ]
Sakao, Seiichiro [1 ]
Suzuki, Takuji [1 ]
机构：
[1] Chiba Univ, Grad Sch Med, Dept Respirol, Chiba, Japan
[2] Kameda Med Ctr, Dept Cardiol, Kamogawa, Japan
来源：
INTERNAL MEDICINE | 2023年 / 62卷 / 02期
关键词：
acute myeloid leukemia (AML); hematopoietic stem cell transplantation (HSCT); pulmonary veno-occlusive disease (PVOD); HYPERTENSION; PATIENT;
D O I：
10.2169/internalmedicine.9811-22
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We herein report a case of pulmonary veno-occlusive disease (PVOD) induced by allo-hematopoietic stem cell transplantation (HSCT) in a 48-year-old man who was diagnosed with acute myeloid leukemia. Five months after transplantation, he developed dyspnea and was diagnosed with pulmonary hypertension based on right heart catheterization. Although he received treatment with pulmonary vasodilators, diuretics, and cor-ticosteroids, his pulmonary artery pressure did not decrease, and his pulmonary edema worsened. Based on the clinical course, hypoxemia, diffusion impairment, and computed tomography findings, the patient was di-agnosed with HSCT-related PVOD. Critical attention should be paid to dyspnea after HSCT for the early di-agnosis of PVOD.
引用
收藏
页码：275 / 279
页数：5
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