Assessment of Chemical Composition and In Vitro Antioxidant, Antidiabetic, Anticholinesterase and Microbial Virulence-Quenching Effects of Salad Burnet (Sanguisorba minor L.) Harvested from Algeria

被引：6

作者：

Haouam, Chahrazed ^{[1
]}

Boudiba, Sameh ^{[1
]}

Tamfu, Alfred Ngenge ^{[2
,3
,4
]}

Kucukaydin, Selcuk ^{[4
,5
]}

Hanini, Karima ^{[1
]}

Zohra, Haouaouchi Fatma ^{[1
,6
]}

Hioun, Soraya ^{[7
]}

Botezatu, Andreea Dediu ^{[8
]}

Ceylan, Ozgur ^{[3
]}

Boudiba, Louiza ^{[1
]}

Duru, Mehmet Emin ^{[4
]}

Dinica, Rodica Mihaela ^{[8
]}

机构：

[1] Echahid Cheikh Larbi Tebessi Univ, Lab Appl Chem & Renewable Energies LACRE, Constantine Rd, Tebessa 12002, Algeria

[2] Univ Ngaoundere, Sch Chem Engn & Mineral Ind, Dept Chem Engn, Ngaoundere 454, Cameroon

[3] Mugla Sitki Kocman Univ, Ula Ali Kocman Vocat Sch, Food Qual Control & Anal Program, TR-48147 Mugla, Turkiye

[4] Mugla Sitki Kocman Univ, Fac Sci, Dept Chem, TR-48121 Mugla, Turkiye

[5] Mugla Sitki Kocman Univ, Koycegiz Vocat Sch Hlth Serv, Dept Med Serv & Tech, TR-48800 Koycegiz Mugla, Turkiye

[6] Echahid Cheikh Larbi Tebessi Univ, Lab Organ Mat & Heterochem LOMH, Constantine Rd, Tebessa 12002, Algeria

[7] Echahid Cheikh Larbi Tebessi Univ, Dept Nat & Life Sci FSESNV, Constantine Rd, Tebessa 12002, Algeria

[8] Dunarea de Jos Univ Galati, Fac Sci & Environm, Dept Chem Phys & Environm, 47 Domneasca Str, Galati 800008, Romania

来源：

PLANTS-BASEL | 2023年 / 12卷 / 24期

关键词：

Sanguisorba minor; chemical composition; antioxidant activity; antibiofilm properties; anticholinesterase activity; antidiabetic potential; WILD EDIBLE PLANTS; PHENOLIC-COMPOUNDS; MEDICINAL-PLANTS; INHIBITION; ANTIBIOFILM; POLYPHENOLS; MECHANISMS; BEVERAGES; DISEASE; FOODS;

D O I：

10.3390/plants12244134

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Sanguisorba minor is a medicinal vegetable used in seasoning desserts, juices, and beverages. An evaluation of the total flavonoid, phenolic, tannin and anthocyanin contents indicated that these classes of compounds are distributed variably in the different fractions. In summary, the HPLC-DAD analyses enabled the identification and quantification of thirteen phenolic compounds in an ethyl acetate extract (EAE), nine in a dichloromethane extract (DCME), seven in an aqueous extract (AQE) and four in a butanol extract (BE). Rutin was the most abundant phenolic compound in the BE (278.4 +/- 1.20 mu g/g) and AQE (32.87 +/- 0.23 mu g/g) fractions, while apigenin was the most abundant in the DCME (84.75 +/- 0.60 mu g/g) and EAE (156.8 +/- 0.95 mu g/g) fractions. The presence of phenolic compounds in the fractions conferred good antioxidant capacity, especially the EAE and DCME fractions, which both exhibited higher antioxidant effects than BHA and alpha-tocopherol in DPPH center dot and CUPRAC assays. Additionally, in the ABTS(center dot+) assay, EAE (IC50 = 9.27 +/- 0.33 mu g/mL) was more active than alpha-tocopherol (IC50 = 35.50 +/- 0.55 mu g/mL), and BHA (IC50 = 12.70 +/- 0.10 mu g/mL). At 200 mu g/mL, the fractions inhibited acetylcholinesterase and butyrylcholinesterase as well as alpha-amylase and alpha-glucosidase, indicating that they can slow neurodegeneration and hyperglycemia. Minimal inhibitory concentration (MIC) values ranged from 0.312 mg/mL to 1.25 mg/mL, and fractions showed good biofilm inhibition against Staphylococcus aureus and Escherichia coli. The extracts exhibited good violacein inhibition in Chromobacterium violaceum CV12472 and Chromobacterium violaceum CV026, despite the supply of external acyl-homoserine lactone to CV026. The antioxidant, quorum-sensing, antibiofilm and enzyme inhibition attributes indicate the potential for the application of S. minor as a food preservative.

引用

页数：22

共 1 条

[1] Chemical Composition, Antioxidant, Antiobesity, and Antidiabetic Effects ofHelichrysum sanguineum (L.) Kostel. from Palestine
Jaradat, Nidal
Qneibi, Mohammad
Hawash, Mohammed
Sawalha, Anood
Qtaishat, Sana
Hussein, Fatima
Issa, Linda
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING, 2021, 46 (01) : 41 - 51

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