Maternal Influenza and Offspring Neurodevelopment

被引：5

作者：

Egorova, Marya ^{[1
]}

Egorov, Vladimir ^{[1
,2
]}

Zabrodskaya, Yana ^{[1
,3
]}

机构：

[1] Russian Minist Hlth, Smorodintsev Res Inst Influenza, 15-17 Ulitsa Prof Popova, St Petersburg 197376, Russia

[2] Inst Expt Med, 12 Ulitsa Akad Pavlova, St Petersburg 197376, Russia

[3] Peter Great St Petersburg Polytech Univ, Inst Biomed Syst & Biotechnol, 29 Ulitsa Polytech Skaya, St Petersburg 194064, Russia

来源：

CURRENT ISSUES IN MOLECULAR BIOLOGY | 2024年 / 46卷 / 01期

关键词：

maternal influenza infection; immune system; neurodevelopment; neuropsychiatric disorders; animal models; infectious diseases; pregnancy; PRENATAL IMMUNE ACTIVATION; HUMAN GESTATIONAL TISSUES; VIRAL GENE REPLICATION; VIRUS-INFECTION; CYTOKINE PRODUCTION; DOPAMINERGIC HYPERFUNCTION; PROINFLAMMATORY CYTOKINES; BRAIN-DEVELOPMENT; PROVED VIREMIA; FETAL EXPOSURE;

D O I：

10.3390/cimb46010023

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review examines the complex interactions between maternal influenza infection, the immune system, and the neurodevelopment of the offspring. It highlights the importance of high-quality studies to clarify the association between maternal exposure to the virus and neuropsychiatric disorders in the offspring. Additionally, it emphasizes that the development of accurate animal models is vital for studying the impact of infectious diseases during pregnancy and identifying potential therapeutic targets. By drawing attention to the complex nature of these interactions, this review underscores the need for ongoing research to improve the understanding and outcomes for pregnant women and their offspring.

引用

页码：355 / 366

页数：12

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