Diagnostic performance of wide-field optical coherence tomography angiography in detecting open-angle glaucoma in high myopia

被引：3

作者：

Zhang, Yinhang ^{[1
]}

Wang, Deming ^{[1
]}

Lin, Fengbin ^{[1
]}

Song, Yunhe ^{[1
]}

Chen, Yu ^{[1
]}

Peng, Yuying ^{[1
]}

Chen, Meiling ^{[1
]}

Liu, Yuhong ^{[1
]}

Jiang, Jiaxuan ^{[1
]}

Yang, Zefeng ^{[1
]}

Li, Fei ^{[1
,2
]}

Zhang, Xiulan ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, Guangdong Prov Clin Res Ctr Ocular Dis, State Key Lab Ophthalmol,Guangdong Prov Key Lab O, Guangzhou, Peoples R China

[2] Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, Guangdong Prov Clin Res Ctr Ocular Dis, State Key Lab Ophthalmol,Guangdong Prov Key Lab O, Guangzhou 510060, Peoples R China

来源：

ACTA OPHTHALMOLOGICA | 2024年 / 102卷 / 02期

基金：

中国国家自然科学基金;

关键词：

capillary density; diagnostic performance; high myopia; open-angle glaucoma; optical coherence tomography angiography; wide-field; VISUAL-FIELD; EYES; CLASSIFICATION; PARAMETERS; ACCURACY; DEFECTS; IMAGES; MAP;

D O I：

10.1111/aos.16603

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To compare the diagnostic performance of the capillary density (CD) of the central 1-6 mm and peripheral 6-12 mm annular regions in detecting open-angle glaucoma in high myopia (HM) using 15 x 12 mm wide-field swept-source optical coherence tomography angiography (WF SS-OCTA).Methods: The study enrolled 206 and 103 eyes with HM and highly myopic open-angle glaucoma (HM-OAG), respectively. WF SS-OCTA images centred on the fovea were obtained to analyse the changes in the CD in the 1-3 mm, 3-6 mm, 6-9 mm, and 9-12 mm annular regions. CD of the superficial capillary plexus (SCP) was measured with the built-in software. The area under the receiver operating characteristic curve (AUROC) of each region was compared.Results: The diagnostic performance of the SCP CD in the central 1-6 mm annular region (AUROC = 0.849) was better than that in the peripheral 6-12 mm annular region (AUROC = 0.756, p = 0.001). The annular AUROCs of SCP CD peaked in the 3-6 mm annular region (AUROC = 0.858) and gradually decreased with increasing diameter and were lower than the corresponding AUROCs of the ganglion cell-inner plexiform layer thickness (p < 0.05 for all comparisons). SCP CD of the inferior quadrant in the 3-6 mm annular region had the best diagnostic performance (AUROC = 0.859).Conclusion: The SCP CD in the central 1-6 mm annular region exhibited better diagnostic performance for the detection of HM-OAG in HM. The assessment of more peripheral regions has no added value in detecting glaucoma in HM.

引用

页码：E168 / E177

页数：10