MicroRNA-155 is a main part of proinflammatory puzzle during severe coronavirus disease 2019 (COVID-19)

被引：4

作者：

Asadpour-Behzadi, Asieh ^{[1
]}

Kariminik, Ashraf ^{[1
]}

Kheirkhah, Babak ^{[2
]}

机构：

[1] Islamic Azad Univ, Dept Microbiol, Kerman Branch, Kerman, Iran

[2] Islamic Azad Univ, Dept Vet Med, Baft Branch, Baft, Iran

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2023年 / 51卷 / 02期

关键词：

SARS-CoV-2; Coronavirus Disease 2019; MiR-155; Inflammation; IMMUNE-RESPONSE; MIR-155; EXPRESSION; REGULATOR; INJURY; GENES;

D O I：

10.15586/aei.v51i2.698

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Genetic and epigenetic parameters play critical roles in determining the outcomes of the severe acute respiratory syndrome coronavirus type 19 (SARS-CoV-2) infection. MicroRNAs (miRNAs) are an important part of the epigenetic factors that regulate several functions of the immune cells and also viruses. Accordingly, the molecules can regulate expression of the immune cell proteins and virus in the host cells. Among the miRNAs, miRNA-155 (miR-155) is well-studied in patients suffering from severe coronavirus disease 2019 (COVID-19). It has been reported that the SARS-CoV-2 infected patients may be directed to induce a cytokine storm or severe proinflammatory responses. This review article discusses the pathological roles of miR-155 during COVID-19 infection. (c) 2023 Codon Publications. Published by Codon Publications.

引用

页码：115 / 119

页数：5

共 42 条

[41] COVID-19 diagnosis - A review of current methods [J].

Yuce, Meral ;

Filiztekin, Elif ;

Ozkaya, Korin Gasia .

BIOSENSORS & BIOELECTRONICS, 2021, 172

[42] Silencing MicroRNA-155 Attenuates Cardiac Injury and Dysfunction in Viral Myocarditis via Promotion of M2 Phenotype Polarization of Macrophages [J].

Zhang, Yingying ;

Zhang, Mengying ;

Li, Xueqin ;

Tang, Zongsheng ;

Wang, Xiangmin ;

Zhong, Min ;

Suo, Qifeng ;

Zhang, Yao ;

Lv, Kun .

SCIENTIFIC REPORTS, 2016, 6

← 1 2 3 4 5 →