Purpose of ReviewAlthough fertility preservation is not yet fully integrated into the comprehensive cancer care of pediatric and adolescent patients, advances continue to take place. This review summarizes recent updates and trends for health care professionals caring for these patients.Recent FindingsThe creation of standardized infertility risk assessment guidelines offers the opportunity to provide greater consistency in clinical care and to provide a current baseline for future research studies seeking to refine risk stratification for individual patients. New agents are being introduced into cancer care; as their use increases, information about their impact on fertility is being studied. Ovarian tissue cryopreservation offers a new standard of care option for fertility preservation, but additional studies are needed to further assess efficacy and impact on ovarian reserve among pediatric and adolescent patients. Standardization of fertility preservation recommendations among certain sub-populations may also make it easier to provide greater consistency in clinical care.Advances continue to be made in the field of fertility preservation, but dissemination of this information is critical to moving toward fertility preservation truly being a part of comprehensive cancer care.
机构:
Sun Yat Sen Univ, Affiliated Hosp 1, Reprod Med Ctr, Guangzhou, Peoples R ChinaSun Yat Sen Univ, Affiliated Hosp 1, Reprod Med Ctr, Guangzhou, Peoples R China
Chen, Lin
Dong, Zirui
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Chinese Univ Hong Kong, Dept Obstet & Gynecol, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R ChinaSun Yat Sen Univ, Affiliated Hosp 1, Reprod Med Ctr, Guangzhou, Peoples R China
Dong, Zirui
Chen, Xiaoyan
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Shenzhen Univ, Shenzhen Baoan Womens & Childrens Hosp, Maternal Fetal Med Inst, Shenzhen, Peoples R China
Chinese Univ Hong Kong, Fertil Preservat Res Ctr, Dept Obstet & Gynecol, Hong Kong, Peoples R ChinaSun Yat Sen Univ, Affiliated Hosp 1, Reprod Med Ctr, Guangzhou, Peoples R China
机构:
Michigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Michigan State Univ, Helen DeVos Childrens Hosp, Coll Human Med, 100 Michigan St NE, Grand Rapids, MI 49503 USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Close, Allison
Burns, Karen
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Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Dept Pediat,Sch Med, Cincinnati, OH USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Burns, Karen
Bjornard, Kari
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Indiana Univ Sch Med, Dept Pediat, Div Hematol Oncol, Indianapolis, IN USA
Riley Hosp Children Indiana Univ Hlth, Indianapolis, IN USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Bjornard, Kari
Webb, Martine
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Univ Calif Los Angeles, Div Internal Med, Los Angeles, CA USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Webb, Martine
Chavez, Josuah
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机构:
Helen DeVos Childrens Hosp, Div Hematol Oncol, Grand Rapids, MI USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Chavez, Josuah
Chow, Eric J.
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Seattle Childrens Hosp, Fred Hutchinson Canc Ctr, Seattle, WA USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
Chow, Eric J.
Meacham, Lillian
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Emory Univ Atlanta, Aflac Canc & Blood Disorders Ctr, Pediat Hematol Oncol BMT, Atlanta, GA USAMichigan State Univ, Helen DeVos Childrens Hosp, Div Hematol Oncol, Coll Human Med, Grand Rapids, MI USA
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Northwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Surg, 225 East Chicago Ave Box 63, Chicago, IL 60611 USANorthwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Harris, Courtney J.
Corkum, Kristine S.
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Northwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Surg, 225 East Chicago Ave Box 63, Chicago, IL 60611 USANorthwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Corkum, Kristine S.
Laronda, Monica M.
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Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Surg, 225 East Chicago Ave Box 63, Chicago, IL 60611 USA
Ann & Robert H Lurie Childrens Hosp Chicago, Stanley Manne Childrens Res Inst, Chicago, IL 60611 USANorthwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Laronda, Monica M.
Rowell, Erin E.
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Northwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Surg, 225 East Chicago Ave Box 63, Chicago, IL 60611 USANorthwestern Univ, Dept Surg, Feinberg Sch Med, Chicago, IL 60611 USA
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Univ Calif San Diego, Dept Obstet Gynecol & Reprod Sci, La Jolla, CA USAUniv Calif San Diego, Dept Obstet Gynecol & Reprod Sci, La Jolla, CA USA
Yang, Emily H.
Strohl, Harmonie B.
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Univ Calif San Diego, Sch Med, La Jolla, CA USAUniv Calif San Diego, Dept Obstet Gynecol & Reprod Sci, La Jolla, CA USA
Strohl, Harmonie B.
Su, H. Irene
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Univ Calif San Diego, Moores Canc Ctr, Dept Obstet Gynecol & Reprod Sci, Div Reprod Endocrinol & Infertil, La Jolla, CA 92093 USAUniv Calif San Diego, Dept Obstet Gynecol & Reprod Sci, La Jolla, CA USA
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Univ Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Moravek, Molly B.
Appiah, Leslie C.
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Ohio State Univ, Dept Obstet & Gynecol, Sect Pediat & Adolescent Gynecol, Div Gen Obstet & Gynecol,Nationwide Childrens Hos, Columbus, OH 43210 USA
James Canc Ctr, Columbus, OH USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Appiah, Leslie C.
Anazodo, Antoinette
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Sydney Childrens Hosp, Kids Canc Ctr, Sydney, NSW, Australia
Prince Wales Hosp, Nelune Comprehens Canc Ctr, Sydney, NSW, Australia
Univ New South Wales, Sch Womens & Childrens, Sydney, NSW, AustraliaUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Anazodo, Antoinette
Burns, Karen C.
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Univ Cincinnati, Coll Med, Dept Pediat,Med Ctr, Div Oncol,Canc & Blood Dis Inst,Cincinnati Childr, Cincinnati, OH USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Burns, Karen C.
Gomez-Lobo, Veronica
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Georgetown Univ, Childrens Natl Med Ctr, Washington Hosp Ctr, Div Pediat & Adolescent Gynecol, Washington, DC USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Gomez-Lobo, Veronica
Hoefgen, Holly R.
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Washington Univ, Sch Med, Div Pediat & Adolescent Gynecol, St Louis, MO USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Hoefgen, Holly R.
Frias, Olivia Jaworek
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Cincinnati Childrens Hosp Med Ctr, Comprehens Fertil Care & Preservat Program, Div Pediat & Adolescent Gynecol, Cincinnati, OH 45229 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Frias, Olivia Jaworek
Laronda, Monica M.
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Ann & Robert H Lurie Childrens Hosp, Chicago, IL USA
Northwestern Univ, Dept Pediat, Div Endocrinol, Chicago, IL 60611 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Laronda, Monica M.
Levine, Jennifer
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Weill Cornell Med, Div Pediat Hematol & Oncol, New York, NY USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Levine, Jennifer
Meacham, Lillian R.
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Childrens Healthcare Atlanta, Aflac Canc Ctr, Atlanta, GA USA
Emory Univ, Dept Pediat, Div Hematol Oncol & Endocrinol, Atlanta, GA 30322 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Meacham, Lillian R.
Pavone, Mary Ellen
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机构:
Northwestern Univ, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Chicago, IL 60611 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Pavone, Mary Ellen
Quinn, Gwendolyn P.
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NYU, Dept Obstet & Gynecol, Div Med Eth, New York, NY 10016 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Quinn, Gwendolyn P.
Rowell, Erin E.
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机构:
Ann & Robert H Lurie Childrens Hosp, Chicago, IL USA
Northwestern Univ, Dept Pediat Surg, Chicago, IL 60611 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Rowell, Erin E.
Strine, Andrew C.
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Cincinnati Childrens Hosp Med Ctr, Div Urol, Cincinnati, OH 45229 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Strine, Andrew C.
Woodruff, Teresa K.
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Northwestern Univ, Dept Obstet & Gynecol, Feinberg Sch Med, Chicago, IL 60611 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA
Woodruff, Teresa K.
Nahata, Leena
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机构:
Ohio State Univ, Dept Pediat, Div Endocrinol, Nationwide Childrens Hosp, Columbus, OH 43210 USA
Ohio State Univ, Ctr Biobehav Hlth, Nationwide Childrens Hosp, Columbus, OH 43210 USAUniv Michigan, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Ann Arbor, MI 48109 USA