We study a class of adversarial minimum-cost flow problems where the arcs are subject to multiple ripple effect disruptions that increase their usage cost. The locations of the disruptions' epicenters are uncertain, and the decision maker seeks a flow that mini-mizes cost assuming the worst-case realization of the disruptions. We evaluate the damage to each arc using a linear model, where the damage is the cumulative damage of all disrup-tions affecting the arc; and a maximum model, where the damage is given by the most destructive disruption affecting the arc. For both models, the arcs' costs after disruptions are represented with a mixed-integer feasible region, resulting in a robust optimization problem with a mixed-integer uncertainty set. The main challenge to solve the problem comes from a subproblem that evaluates the worst-case cost for a given flow plan. We show that for the linear model the uncertainty set can be decomposed into a series of single disruption problems, which leads to a polynomial time algorithm for the subproblem. The uncertainty set of the maximum model, however, cannot be decomposed, and we show that the subproblem under this model is NP-hard. For this case, we further present a big-M free binary reformulation of the uncertainty set based on conflict constraints that results in a significantly smaller formulation with tighter linear programming relaxations. We extend the models by considering a less conservative approach where only a subset of the disrup-tions can occur and show that the properties of the linear and maximum models also hold in this case. We test our proposed approaches over real road networks and synthetics instances and show that our methods achieve orders of magnitude improvements over a standard approach from the literature.
