Disinhibition of short-latency but not long-latency afferent inhibition of the lower limb during upper-limb muscle contraction

被引:0
作者
Kato, Tatsuya [1 ,2 ]
Sasaki, Atsushi [1 ,2 ,3 ]
Nakazawa, Kimitaka [1 ]
机构
[1] Univ Tokyo, Grad Sch Arts & Sci, Dept Life Sci, 3-8-1 Komaba,Meguro Ku, Tokyo 1538902, Japan
[2] Japan Soc Promot Sci, Tokyo, Japan
[3] Osaka Univ, Grad Sch Engn Sci, Dept Mech Sci & Bioengn, Osaka, Japan
基金
日本学术振兴会;
关键词
Hoffman reflex; interlimb; long-latency afferent inhibition; sensorimotor integration; short-latency afferent inhibition; transcranial magnetic stimulation; SOMATOSENSORY EVOKED-POTENTIALS; MOTOR CORTEX; MEDIAN NERVE; SENSORIMOTOR INTEGRATION; HAND; EXCITABILITY; STIMULATION; MODULATION; ATTENTION; CIRCUITS;
D O I
10.1097/WNR.0000000000001889
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Research has demonstrated that motor and sensory functions of the lower limbs can be modulated by upper-limb muscle contractions. However, whether sensorimotor integration of the lower limb can be modulated by upper-limb muscle contractions is still unknown. [AQ: NR Original articles do not require structured abstracts. Hence, abstract subsections have been deleted. Please check.]Human sensorimotor integration has been studied using short- or long-latency afferent inhibition (SAI or LAI, respectively), which refers to inhibition of motor-evoked potentials (MEPs) elicited via transcranial magnetic stimulation by preceding peripheral sensory stimulation. In the present study, we aimed to investigate whether upper-limb muscle contractions could modulate the sensorimotor integration of the lower limbs by examining SAI and LAI. Soleus muscle MEPs following electrical tibial nerve stimulation (TSTN) during rest or voluntary wrist flexion were recorded at inter-stimulus intervals (ISIs) of 30 (i.e. SAI), 100, and 200 ms (i.e. LAI). The soleus Hoffman reflex following TSTN was also measured to identify whether MEP modulation occurred at the cortical or the spinal level. Results showed that lower-limb SAI, but not LAI, was disinhibited during voluntary wrist flexion. Furthermore, the soleus Hoffman reflex following TSTN during voluntary wrist flexion was unchanged when compared with that during the resting state at any ISI. Our findings suggest that upper-limb muscle contractions modulate sensorimotor integration of the lower limbs and that disinhibition of lower-limb SAI during upper-limb muscle contractions is cortically based.
引用
收藏
页码:280 / 286
页数:7
相关论文
共 47 条
  • [1] PROPRIOCEPTIVE MODULATION OF SOMATOSENSORY EVOKED-POTENTIALS DURING ACTIVE OR PASSIVE FINGER MOVEMENTS IN MAN
    ABBRUZZESE, G
    RATTO, S
    FAVALE, E
    ABBRUZZESE, M
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1981, 44 (10) : 942 - 949
  • [2] THE RELATIONSHIP BETWEEN HUMAN LONG-LATENCY SOMATOSENSORY EVOKED-POTENTIALS RECORDED FROM THE CORTICAL SURFACE AND FROM THE SCALP
    ALLISON, T
    MCCARTHY, G
    WOOD, CC
    [J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1992, 84 (04): : 301 - 314
  • [3] HUMAN CORTICAL POTENTIALS-EVOKED BY STIMULATION OF THE MEDIAN NERVE .2. CYTOARCHITECTONIC AREAS GENERATING LONG-LATENCY ACTIVITY
    ALLISON, T
    MCCARTHY, G
    WOOD, CC
    WILLIAMSON, PD
    SPENCER, DD
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1989, 62 (03) : 711 - 722
  • [4] ASANUMA H, 1984, J NEUROPHYSIOL, V52, P212, DOI 10.1152/jn.1984.52.2.212
  • [5] Short-latency afferent inhibition determined by the sensory afferent volley
    Bailey, Aaron Z.
    Asmussen, Michael J.
    Nelson, Aimee J.
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2016, 116 (02) : 637 - 644
  • [6] Modulation of motor cortex excitability by median nerve and digit stimulation
    Chen, R
    Corwell, B
    Hallett, M
    [J]. EXPERIMENTAL BRAIN RESEARCH, 1999, 129 (01) : 77 - 86
  • [7] Dynamic modulation of corticospinal excitability and short-latency afferent inhibition during onset and maintenance phase of selective finger movement
    Cho, Hyun Joo
    Panyakaew, Pattamon
    Thirugnanasambandam, Nivethida
    Wu, Tianxia
    Hallett, Mark
    [J]. CLINICAL NEUROPHYSIOLOGY, 2016, 127 (06) : 2343 - 2349
  • [8] CRONE C, 1990, EXP BRAIN RES, V81, P35
  • [9] Effect of the brain-derived neurotrophic factor gene Val66Met polymorphism on sensory-motor integration during a complex motor learning exercise
    Deveci, Sule
    Matur, Zeliha
    Kesim, Yesim
    , Gokce Senturk
    Sargin-Kurt, Gulcan
    , Sibel Aylin Ugur
    , Ali Emre Oge
    [J]. BRAIN RESEARCH, 2020, 1732
  • [10] Segregating two inhibitory circuits in human motor cortex at the level of GABAA receptor subtypes: A TMS study
    Di Lazzaro, V.
    Pilato, F.
    Dileone, M.
    Profice, P.
    Ranieri, F.
    Ricci, V.
    Bria, P.
    Tonali, P. A.
    Ziernann, U.
    [J]. CLINICAL NEUROPHYSIOLOGY, 2007, 118 (10) : 2207 - 2214