COVID-19 does not impact on outcome of myeloma patients infected while undergoing autologous stem cell transplantation

被引:0
作者
Masina, Lorenzo [1 ]
Bianchetti, Nicola [1 ]
Passi, Angela [1 ]
Bottelli, Chiara [1 ]
Bagnasco, Samuele [1 ]
Spolzino, Angelica [1 ]
Oberti, Margherita [1 ]
Chiarini, Marco [2 ]
Belotti, Angelo [1 ]
Voltolini, Simone [3 ]
Faglioni, Laura [3 ]
Rossi, Giuseppe [1 ]
Tucci, Alessandra [1 ]
Cattaneo, Chiara [1 ]
机构
[1] ASST Spedali Civili, Haematol, Ple Spedali Civili 1, I-25123 Brescia, Italy
[2] ASST Spedali Civili Brescia, Clin Chem Lab, Flow Cytometry Unit, Brescia, Italy
[3] Azienda Osped Carlo Poma, Oncol Dept, Mantua, Italy
关键词
autologous stem cell transplantation; COVID-19; myeloma; outcome; MALIGNANCIES;
D O I
10.1002/hon.3127
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Here we report two cases of myeloma patients who became positive for SARS-CoV-2 infection during the acute phase of autologous stem cell transplant. Both patients were promptly treated with monoclonal antibodies and remdesivir, and, despite the profound neutropenia and lymphopenia, they did not develop respiratory failure and they remained paucisymptomatic during the entire period of aplasia. Neutrophil engraftment took place as expected and the patients were discharged quickly and did not experience adverse effects after discharge.
引用
收藏
页码:555 / 558
页数:4
相关论文
共 10 条
  • [1] High mortality in fully vaccinated hematologic patients treated with anti-CD20 antibodies during the "Omicron wave" of COVID-19 pandemic
    Cattaneo, Chiara
    Masina, Lorenzo
    Pagani, Chiara
    Cancelli, Valeria
    Daffini, Rosa
    Tucci, Alessandra
    Rossi, Giuseppe
    [J]. HEMATOLOGICAL ONCOLOGY, 2023, 41 (01) : 205 - 207
  • [2] Remdesivir Decreases Mortality in COVID-19 Patients with Active Malignancy
    Jaroszewicz, Jerzy
    Kowalska, Justyna
    Pawlowska, Malgorzata
    Rogalska, Magdalena
    Zarebska-Michaluk, Dorota
    Rorat, Marta
    Lorenc, Beata
    Czupryna, Piotr
    Sikorska, Katarzyna
    Piekarska, Anna
    Dworzanska, Anna
    Zaleska, Izabela
    Mazur, Wlodzimierz
    Kozielewicz, Dorota
    Klos, Krzysztof
    Podlasin, Regina
    Angielski, Grzegorz
    Oczko-Grzesik, Barbara
    Figlerowicz, Magdalena
    Szetela, Bartosz
    Bolewska, Beata
    Franczak-Chmura, Paulina
    Flisiak, Robert
    Tomasiewicz, Krzysztof
    [J]. CANCERS, 2022, 14 (19)
  • [3] The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
    Ljungman, Per
    Mikulska, Malgorzata
    de la Camara, Rafael
    Basak, Grzegorz W.
    Chabannon, Christian
    Corbacioglu, Selim
    Duarte, Rafael
    Dolstra, Harry
    Lankester, Arjan C.
    Mohty, Mohamad
    Montoto, Silvia
    Murray, John
    de Latour, Regis Peffault
    Snowden, John A.
    Yakoub-Agha, Ibrahim
    Verhouven, Bregje
    Kroeger, Nicolaus
    Styczynski, Jan
    [J]. BONE MARROW TRANSPLANTATION, 2020, 55 (11) : 2071 - 2076
  • [4] Immune reconstitution and severity of COVID-19 among hematopoietic cell transplant recipients
    Malek, Alexandre E.
    Adachi, Javier A.
    Mulanovich, Victor E.
    Sassine, Joseph
    Raad, Issam I.
    McConn, Kelly
    Seiler, Garret T.
    Dhal, Udit
    Khawaja, Fareed
    Chemaly, Roy F.
    [J]. TRANSPLANT INFECTIOUS DISEASE, 2021,
  • [5] Neutralizing monoclonal antibodies in haematological patients paucisymptomatic for COVID-19: The GIMEMA EMATO-0321 study
    Marasco, Vincenzo
    Piciocchi, Alfonso
    Candoni, Anna
    Pagano, Livio
    Guidetti, Anna
    Musto, Pellegrino
    Bruna, Riccardo
    Bocchia, Monica
    Visentin, Andrea
    Turrini, Mauro
    Tucci, Alessandra
    Pilerci, Sofia
    Fianchi, Luana
    Salvini, Marco
    Galimberti, Sara
    Coviello, Elisa
    Selleri, Carmine
    Luppi, Mario
    Crea, Enrico
    Fazi, Paola
    Passamonti, Francesco
    Corradini, Paolo
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2022, 199 (01) : 54 - 60
  • [6] COVID-19 during Early Phase of Autologous Stem Cell Transplantation
    Milczarek, Slawomir
    Baumert, Bartlomiej
    Sobus, Anna
    Wilk-Milczarek, Ewa
    Sommerfeld, Krzysztof
    Osekowska, Bogumila
    Borowiecka, Ewa
    Paczkowska, Edyta
    Lanocha, Aleksandra
    Poncyliusz, Wojciech
    Jarosz, Konrad
    Machalinski, Boguslaw
    [J]. MEDICINA-LITHUANIA, 2021, 57 (07):
  • [7] COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA
    Pagano, Livio
    Salmanton-Garc, Jon
    Marchesi, Francesco
    Lopez-Garcia, Alberto
    Lamure, Sylvain
    Itri, Federico
    Gomes-Silva, Maria
    Dragonetti, Giulia
    Falces-Romero, Iker
    van Doesum, Jaap
    Sili, Uluhan
    Labrador, Jorge
    Calbacho, Maria
    Bilgin, Yavuz M.
    Weinbergerova, Barbora
    Serrano, Laura
    Susana, Jose-Maria Ribera-Santa
    Malak, Sandra
    Loureiro-Amigo, Jose
    Glenthoj, Andreas
    Cordoba-Mascunano, Raul
    Nunes-Rodrigues, Raquel
    Gonzalez-Lopez, Tomas-Jose
    Karlsson, Linda Katharina
    Jimenez-Lorenzo, Maria-Josefa
    Hernandez-Rivas, Jose-Angel
    Jaksic, Ozren
    Racil, Zdenek
    Busca, Alessandro
    Corradini, Paolo
    Hoenigl, Martin
    Klimko, Nikolai
    Koehler, Philipp
    Pagliuca, Antonio
    Passamonti, Francesco
    Cornely, Oliver A.
    [J]. BLOOD, 2022, 139 (10) : 1588 - 1592
  • [8] Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study
    Passamonti, Francesco
    Cattaneo, Chiara
    Arcaini, Luca
    Bruna, Riccardo
    Cavo, Michele
    Merli, Francesco
    Angelucci, Emanuele
    Krampera, Mauro
    Cairoli, Roberto
    Della Porta, Matteo Giovanni
    Fracchiolia, Nicola
    Ladetto, Marco
    Passerini, Carlo Gambacorti
    Salvini, Marco
    Marchetti, Monia
    Lemoli, Roberto
    Molteni, Alfredo
    Busca, Alessandro
    Cuneo, Antonio
    Romano, Alessandra
    Giuliani, Nicola
    Galimberti, Sara
    Corso, Alessandro
    Morotti, Alessandro
    Falini, Brunangelo
    Billio, Atto
    Gherlinzoni, Filippo
    Visani, Giuseppe
    Tisi, Maria Chiara
    Tafuri, Agostino
    Tosi, Patrizia
    Lanza, Francesco
    Massaia, Massimo
    Turrini, Mauro
    Ferrara, Felicetto
    Gurrieri, Carmela
    Vallisa, Daniele
    Martelli, Maurizio
    Derenzini, Enrico
    Guarini, Attilio
    Conconi, Annarita
    Cuccaro, Annarosa
    Cudillo, Laura
    Russo, Domenico
    Ciambelli, Fabrizio
    Scattolin, Anna Maria
    Luppi, Mario
    Selleri, Carmine
    La Barbera, Elettra Ortu
    Ferrandina, Celestino
    [J]. LANCET HAEMATOLOGY, 2020, 7 (10): : E737 - E745
  • [9] Immunogenicity of COVID-19 vaccines in patients with hematologic malignancies: a systematic review and meta-analysis
    Teh, Joanne S. K.
    Coussement, Julien
    Neoh, Zoe C. F.
    Spelman, Tim
    Lazarakis, Smaro
    Slavin, Monica A.
    Teh, Benjamin W.
    [J]. BLOOD ADVANCES, 2022, 6 (07) : 2014 - 2034
  • [10] Early report on the severity of COVID-19 in hematologic patients infected with the SARS-CoV2 omicron variant
    Ullrich, Fabian
    Hanoun, Christine
    Turki, Amin T.
    Liebregts, Tobias
    Breuckmann, Katharina
    Alashkar, Ferras
    Reinhardt, Hans Christian
    von Tresckow, Bastian
    von Tresckow, Julia
    [J]. EUROPEAN JOURNAL OF HAEMATOLOGY, 2022, 109 (04) : 364 - 372