Transcutaneous auricular vagus stimulation (taVNS) improves human working memory performance under sleep deprivation stress

被引:10
|
作者
Zhao, Rui [1 ]
Chang, Meng-Ying [1 ]
Cheng, Chen [2 ]
Tian, Qian-Qian [2 ,3 ]
Yang, Xue-Juan [2 ,3 ,4 ]
Du, Meng-Yu [2 ,3 ]
Cui, Ya-Peng [2 ,3 ]
He, Zhao-Yang [1 ]
Wang, Fu-Min [1 ]
Kong, Yao [1 ]
Deng, Hui [2 ,3 ,4 ]
Lu, Li-Ming [5 ]
Tang, Chun-Zhi [5 ]
Xu, Neng-Gui [5 ]
Sun, Jin-Bo [2 ,3 ,4 ]
Qin, Wei [2 ,3 ,4 ]
机构
[1] Xian Polytech Univ, Sch Elect & Informat, Xian, Peoples R China
[2] Xidian Univ, Intelligent Non Invas Neuromodulat Technol & Trans, Xian 710126, Shaanxi, Peoples R China
[3] Xidian Univ, Engn Res Ctr Mol & Neuro Imaging, Sch Life Sci & Technol, Minist Educ, Xian 710126, Shaanxi, Peoples R China
[4] Xidian Univ, Guangzhou Inst Technol, Xian 710126, Shaanxi, Peoples R China
[5] Guangzhou Univ Chinese Med, Med Coll Acu Moxi & Rehabil, South China Res Ctr Acupuncture & Moxibust, Guangzhou, Peoples R China
基金
美国国家科学基金会; 国家重点研发计划;
关键词
TaVNS; Working memory; Sleep deprivation; Fatigue countermeasure; Non-invasive neuromodulation; COERULEUS-NORADRENERGIC SYSTEM; NERVE-STIMULATION; LOCUS-COERULEUS; INDIVIDUAL-DIFFERENCES; NOREPINEPHRINE; CORTEX; NIGHT; EXCITABILITY; METAANALYSIS; ACTIVATION;
D O I
10.1016/j.bbr.2022.114247
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Many human activities require high cognitive performance over long periods, while impairments induced by sleep deprivation influence various aspects of cognitive abilities, including working memory (WM), attention, and processing speed. Based on previous research, vagal nerve stimulation can modulate cognitive abilities, attention, and arousal. Two experiments were conducted to assess the efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) to relieve the deleterious effects of sleep deprivation. In the first experiment, 35 participants completed N-back tasks at 8:00 a.m. for two consecutive days in a within-subject study. Then, the participants received either taVNS or earlobe stimulation (active control) intervention in two sessions at random orders after 24 h of sustained wakefulness. Then, they completed the N-back tasks again. In the second exper-iment, 30 participants completed the psychomotor vigilance task (PVT), and 32 completed the N-back tasks at 8:00 a.m. on the first and second days. Then, they received either taVNS or earlobe stimulation at random orders and finished the N-back and PVT tasks immediately after one hour. In Experiment 1, taVNS could significantly improve the accuracy rate of participants in spatial 3-back tasks compared to active control, which was consistent with experiment 2. However, taVNS did not specifically enhance PVT performance. Therefore, taVNS could be a powerful intervention for acute sleep deprivation as it can improve performance on high cognitive load tasks and is easy to administer.
引用
收藏
页数:13
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