The Potential of Ginkgo biloba as a Source of Biologically Active Compounds-A Review of the Recent Literature and Patents

被引：50
作者：
Biernacka, Patrycja [1 ]
Adamska, Iwona [1 ]
Felisiak, Katarzyna [1 ]
机构：
[1] Technol West Pomeranian Univ Technol, Fac Food Sci & Fisheries, Dept Food Sci, PL-70310 Szczecin, Poland
来源：
MOLECULES | 2023年 / 28卷 / 10期
关键词：
ginkgo biloba; patents; ginkgotoxin; pro-health properties; food industry; P-HYDROXYBENZOIC ACID; LEAF EXTRACT; ANTIOXIDANT PROPERTIES; INFLAMMATORY RESPONSE; ENDOTHELIAL-CELLS; SAFETY ASSESSMENT; CANCER; LEAVES; L; TOXICITY;
D O I：
10.3390/molecules28103993
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Ginkgo biloba is a relict tree species showing high resistance to adverse biotic and abiotic environmental factors. Its fruits and leaves have high medicinal value due to the presence of flavonoids, terpene trilactones and phenolic compounds. However, ginkgo seeds contain toxic and allergenic alkylphenols. The publication revises the latest research results (mainly from 2018-2022) regarding the chemical composition of extracts obtained from this plant and provides information on the use of extracts or their selected ingredients in medicine and food production. A very important section of the publication is the part in which the results of the review of patents concerning the use of Ginkgo biloba and its selected ingredients in food production are presented. Despite the constantly growing number of studies on its toxicity and interactions with synthetic drugs, its health-promoting properties are the reason for the interest of scientists and motivation to create new food products.
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页数：54
相关论文
共 233 条
[91]   Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives [J].
Li, Dan ;
Rui, Yi-Xin ;
Guo, Shi-Duo ;
Luan, Fei ;
Liu, Rong ;
Zeng, Nan .
LIFE SCIENCES, 2021, 284
[92]  
Li F., 2016, Ginkgo Beer Production Method, Patent No. [CN105316145A, 105316145]
[93]   Ginkgetin in vitro and in vivo reduces Streptococcus suis virulence by inhibiting suilysin activity [J].
Li, G. ;
Wang, G. ;
Wang, S. ;
Deng, Y. .
JOURNAL OF APPLIED MICROBIOLOGY, 2019, 127 (05) :1556-1563
[94]  
Li He Li He, 2012, Journal of Medicinal Plants Research, V6, P171, DOI 10.5897/JMPR11.1344
[95]   Anticancer Effects of Five Biflavonoids from Ginkgo Biloba L. Male Flowers In Vitro [J].
Li, Min ;
Li, Bin ;
Xia, Zi-Ming ;
Tian, Ying ;
Zhang, Dan ;
Rui, Wen-Jing ;
Dong, Jun-Xing ;
Xiao, Feng-Jun .
MOLECULES, 2019, 24 (08)
[96]  
Li M, 2019, PHYTOTHER RES, V33, P989, DOI [10.1002/ptr.6292, 10.1109/icems.2019.8922446]
[97]   Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury in a rat model via the TLR4/NF-κB signaling pathway [J].
Li, Qin ;
Ye, Tao ;
Long, Ting ;
Peng, Xuemei .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2019, 83 (04) :675-683
[98]   Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo [J].
Li, Yan ;
Wu, Yannan ;
Yao, Xinlei ;
Hao, Fang ;
Yu, Chunlei ;
Bao, Yongli ;
Wu, Yin ;
Song, Zhenbo ;
Sun, Ying ;
Zheng, Lihua ;
Wang, Guannan ;
Huang, Yanxin ;
Sun, Luguo ;
Li, Yuxin .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (04)
[99]   Hair-growth promoting effect and anti-inflammatory mechanism of Ginkgo biloba polysaccharides [J].
Li, Yingna ;
Sheng, Yu ;
Liu, Jiuyue ;
Xu, Guangyu ;
Yu, Wanwen ;
Cui, Qingwen ;
Lu, Xuechun ;
Du, Peige ;
An, Liping .
CARBOHYDRATE POLYMERS, 2022, 278
[100]   Potential hepatic and renal toxicity induced by the biflavonoids from Ginkgo biloba [J].
Li Yun-Ying ;
Lu Xiao-Yan ;
Sun Jia-Li ;
Wang Qing-Qing ;
Zhang Yao-Dan ;
Zhang Jian-Bing ;
Fan Xiao-Hui .
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 17 (09) :672-681
567891011121314