P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses

被引：1
作者：
Ho, Harvey [1 ]
Zhang, En [2 ]
机构：
[1] Univ Auckland, Auckland Bioengn Inst, Auckland, New Zealand
[2] Chongqing Food & Drug Control Inst, Chongqing, Peoples R China
来源：
FRONTIERS IN PHARMACOLOGY | 2023年 / 14卷
关键词：
methadone; opioids; PBPK; P-glycoprotein; model; IN-VIVO; TRANSPLACENTAL TRANSFER; PLACENTAL-TRANSFER; BUPRENORPHINE; DISPOSITION; METABOLISM; MORPHINE; RAT;
D O I：
10.3389/fphar.2023.1182571
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页数：5
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