This paper considers the problem of inferring the causal effect of a variable Z on a dependently censored survival time T. We allow for unobserved confounding variables, such that the error term of the regression model for T is dependent on the confounded variable Z. Moreover, T is subject to dependent censoring. This means that T is right censored by a censoring time C, which is dependent on T (even after conditioning out the effects of the measured covariates). A control function approach, relying on an instrumental variable, is leveraged to tackle the confounding issue. Further, it is assumed that T and C follow a joint regression model with bivariate Gaussian error terms and an unspecified covariance matrix, such that the dependent censoring can be handled in a flexible manner. Conditions under which the model is identifiable are given, a two-step estimation procedure is proposed, and it is shown that the resulting estimator is consistent and asymptotically normal. Simulations are used to confirm the validity and finite-sample performance of the estimation procedure. Finally, the proposed method is used to estimate the causal effect of job training programs on unemployment duration.
机构:
UCL, Dept Stat Sci, London WC1E 6BT, EnglandLondon Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London WC1, England
Marra, Giampiero
Radice, Rosalba
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London Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London WC1, EnglandLondon Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London WC1, England
机构:
Erasmus MC, Dept Epidemiol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USAErasmus MC, Dept Epidemiol, POB 2040, NL-3000 CA Rotterdam, Netherlands
Swanson, Sonja A.
Hernan, Miguel A.
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Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
Harvard Mit Div Hlth Sci & Technol, Boston, MA USAErasmus MC, Dept Epidemiol, POB 2040, NL-3000 CA Rotterdam, Netherlands
机构:
Inst Stat Math, Dept Stat Data Sci, Tokyo, Japan
Kurume Univ, Biostat Ctr, Kurume, Fukuoka, Japan
Inst Stat Math, Dept Stat Data Sci, Tokyo 1908562, Japan
Kurume Univ, Biostat Ctr, 67 Asahi Machi, Kurume, Fukuoka 8300011, JapanInst Stat Math, Dept Stat Data Sci, Tokyo, Japan
Emura, Takeshi
Ditzhaus, Marc
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Otto von Guericke Univ, Fac Math, Magdeburg, Saxony Anhalt, GermanyInst Stat Math, Dept Stat Data Sci, Tokyo, Japan
Ditzhaus, Marc
Dobler, Dennis
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Vrije Univ Amsterdam, Fac Sci, Dept Math, Amsterdam, North Holland, NetherlandsInst Stat Math, Dept Stat Data Sci, Tokyo, Japan
Dobler, Dennis
Murotani, Kenta
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Kurume Univ, Biostat Ctr, Kurume, Fukuoka, JapanInst Stat Math, Dept Stat Data Sci, Tokyo, Japan