Synthesis of 6,7-dihydro-5H-benzo[c]-1,2,4-triazolo[3,4-a]azepines and 6,7-dihydro-5H-benzo[c]tetrazolo[5,1-a]azepines

被引：0

作者：

Glushkov, Vladimir A. ^{[1
,2
]}

Mosheva, Kseniya A. ^{[1
,2
]}

Zaitsev, Mark M. ^{[2
]}

Pelykh, Vera S. ^{[2
]}

Karasik, Valeriya I. ^{[2
]}

Andreev, Alexander I. ^{[2
]}

Dmitriev, Maksim V. ^{[2
]}

机构：

[1] Ural Branch Russian Acad Sci, Inst Tech Chem, 3 Akademika Koroleva St, Perm 614068, Russia

[2] Perm State Univ, 15 Bukireva St, Perm 614990, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2023年 / 58卷 / 12期

关键词：

benzo[c]azepines; hetarylhydrazines; tetrazolo[5,1-a]azepines; 1,2,4-triazolobenzo[3,4-a]azepines;

D O I：

10.1007/s10593-023-03149-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclization of 1-hydrazinyl-3,3-dimethyl-3,4-tetrahydro-5H-benzo[c]azepine with ethyl orthoformate gave 5,5-dimethyl-6,7-dihydro-5H- benzo[c]-1,2,4-triazolo[3,4-a]azepine, and its reaction with acetic acid afforded 3,5,5-trimethyl-9,10-dimethoxy-6,7-dihydro-5?-benzo[c]-1,2,4-triazolo[3,4-a]azepine. Nitrosation of 1-hydrazino-3,3-dimethyl-3,4-tetrahydro-5H-benzo[c]azepine led to the formation of substituted 6,7-dihydro-5H-benzo[c]tetrazolo[5,1-a]azepines.

引用

页码：727 / 731

页数：5

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