SOX9 Drives KRAS-Induced Lung Adenocarcinoma Progression Through Suppression of Anti-Tumor Immunity

被引：0
|
作者：
Pine, S. R. [1 ]
Zhong, H. [2 ]
Menon, D. Ravindran [1 ]
Ganesan, S. [2 ]
Sabaawy, H. [1 ]
机构：
[1] Univ Colorado, Aurora, CO USA
[2] Rutgers Canc Inst New Jersey, New Brunswick, NJ USA
来源：
JOURNAL OF THORACIC ONCOLOGY | 2023年 / 18卷 / 11期
关键词：
tumor microenvironment; anti-tumor immunity;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OA18.06
引用
收藏
页码：S87 / S87
页数：1
相关论文
共 50 条
  • [21] Pulsatile MEK inhibition improves anti-tumor immunity and T cell function in Kras mutant lung cancer
    Choi, Hyejin
    Deng, Jiehui
    Li, Shuai
    Silk, Tarik
    Dong, Lauren
    Brea, Elliott J.
    Houghton, Sean
    Redmond, David
    Zhong, Hong
    Boiarsky, Jonathan
    Akbay, Esra A.
    Smith, Paul D.
    Merghoub, Taha
    Wong, Kwok-Kin
    Wolchok, Jedd D.
    CANCER RESEARCH, 2020, 80 (16)
  • [22] SAA suppresses α-PD-1 induced anti-tumor immunity by driving TH2 polarization in lung adenocarcinoma
    Wang, Xin
    Wen, Shaodi
    Du, Xiaoyue
    Zhang, Yihan
    Yang, Xiao
    Zou, Renrui
    Feng, Bing
    Fu, Xiao
    Jiang, Feng
    Zhou, Guoren
    Liu, Zi
    Zhu, Wei
    Ma, Rong
    Feng, Jifeng
    Shen, Bo
    CELL DEATH & DISEASE, 2023, 14 (11)
  • [23] SAA suppresses α-PD-1 induced anti-tumor immunity by driving TH2 polarization in lung adenocarcinoma
    Xin Wang
    Shaodi Wen
    Xiaoyue Du
    Yihan Zhang
    Xiao Yang
    Renrui Zou
    Bing Feng
    Xiao Fu
    Feng Jiang
    Guoren Zhou
    Zi Liu
    Wei Zhu
    Rong Ma
    Jifeng Feng
    Bo Shen
    Cell Death & Disease, 14
  • [24] Sox9 mediates Notch pathway-induced epithelial-mesenchymal transition (EMT) in lung adenocarcinoma.
    Capaccione, Kathleen
    Hong, Xuehui
    Morgan, Katherine M.
    Liu, Wenyu
    Allen, Thaddeus
    Bishop, J. Michael
    Pine, Sharon R.
    CLINICAL CANCER RESEARCH, 2014, 20
  • [25] microRNA-133b represses the progression of lung cancer through inhibiting SOX9/β-catenin signaling pathway
    Liu, Shubin
    Li, Shasha
    Yu, Xiaoqiang
    Wang, Qiping
    Sun, Hui
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2020, 13 (09): : 2270 - 2279
  • [26] LOSS OF TUMOR SUPPRESSOR HIC1 ACCELERATES THE PROGRESSION OF LUNG ADENOCARCINOMA INDUCED BY ONCOGENIC KRAS
    Szczepny, Anette
    Jayasekara, Samantha
    Mudiyanselage, Amali
    Watkins, David Neil
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S349 - S349
  • [27] SOX9 drives the epithelial–mesenchymal transition in non-small-cell lung cancer through the Wnt/β-catenin pathway
    Jing-Qiang Huang
    Fa-Kai Wei
    Xiu-Li Xu
    Shi-Xing Ye
    Jun-Wei Song
    Pei-Kun Ding
    Jing Zhu
    He-Feng Li
    Xin-Ping Luo
    Hui Gong
    Li Su
    Lin Yang
    Li-Yun Gong
    Journal of Translational Medicine, 17
  • [28] Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
    Choi, Hyejin
    Deng, Jiehui
    Li, Shuai
    Silk, Tarik
    Dong, Lauren
    Brea, Elliott J.
    Houghton, Sean
    Redmond, David
    Zhong, Hong
    Boiarsky, Jonathan
    Akbay, Esra A.
    Smith, Paul D.
    Merghoub, Taha
    Wong, Kwok-Kin
    Wolchok, Jedd D.
    CELL REPORTS, 2019, 27 (03): : 806 - +
  • [29] SOX9 drives the epithelial-mesenchymal transition in non-small-cell lung cancer through the Wnt/-catenin pathway
    Huang, Jing-Qiang
    Wei, Fa-Kai
    Xu, Xiu-Li
    Ye, Shi-Xing
    Song, Jun-Wei
    Ding, Pei-Kun
    Zhu, Jing
    Li, He-Feng
    Luo, Xin-Ping
    Gong, Hui
    Su, Li
    Yang, Lin
    Gong, Li-Yun
    JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17 (1)
  • [30] Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation
    Weng, Tzu-Yang
    Wu, Hsuan Franziska
    Li, Chung-Yen
    Hung, Yu-Hsuan
    Chang, Yu-Wei
    Chen, Yi-Ling
    Hsu, Hui-Ping
    Chen, Yu-Hung
    Wang, Chih-Yang
    Chang, Jang-Yang
    Lai, Ming-Derg
    SCIENTIFIC REPORTS, 2018, 8
12345