Comparison of Illumination Methods for Flow-Through Optofluidic Biosensors

被引：0
|
作者：
Hamblin, Matthew [1 ]
Wright, Joel [1 ]
Schmidt, Holger [2 ]
Hawkins, Aaron R. [1 ]
机构：
[1] Brigham Young Univ, Elect & Comp Engn, 450 Engn Bldg, Provo, UT 84602 USA
[2] Univ Calif Santa Cruz, Elect & Comp Engn, 1156 High St, Santa Cruz, CA 95064 USA
来源：
MICROMACHINES | 2023年 / 14卷 / 04期
关键词：
optofluidic; lab-on-a-chip; fluorescence; biosensor;
D O I：
10.3390/mi14040723
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Optofluidic biosensors have become an important medical diagnostic tool because they allow for rapid, high-sensitivity testing of small samples compared to standard lab testing. For these devices, the practicality of use in a medical setting depends heavily on both the sensitivity of the device and the ease of alignment of passive chips to a light source. This paper uses a model previously validated by comparison to physical devices to compare alignment, power loss, and signal quality for windowed, laser line, and laser spot methods of top-down illumination.
引用
收藏
页数：14
相关论文
共 50 条
  • [21] An optoelectronic flow-through detectors for active ingredients determination in the pharmaceutical formulations
    Jeber, Jalal N.
    Turkey, Nagham S.
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 201
  • [22] Flow-through immunosensors using antibody-immobilized polymer monoliths
    Liu, Jikun
    Chen, Chien-Fu
    Chang, Chih-Wei
    DeVoe, Don L.
    BIOSENSORS & BIOELECTRONICS, 2010, 26 (01) : 182 - 188
  • [23] Flow-Through Electrochemical Biosensor for the Detection of Listeria monocytogenes Using Oligonucleotides
    Armstrong, Cheryl M.
    Lee, Joe
    Gehring, Andrew G.
    Capobianco, Joseph A.
    SENSORS, 2021, 21 (11)
  • [24] Technical concept of a flow-through microreactor for in-situ RT-PCR
    Felbel, J.
    Reichert, A.
    Kielpinski, M.
    Urban, M.
    Haefner, N.
    Duerst, M.
    Koehler, J. M.
    Weber, J.
    Henkel, T.
    ENGINEERING IN LIFE SCIENCES, 2008, 8 (01): : 68 - 72
  • [25] Flow-through enzyme immobilized amperometric detector for the rapid screening of acetylcholinesterase inhibitors by flow injection analysis
    Vandeput, Marie
    Parsajoo, Cobra
    Vanheuverzwijn, Jerome
    Patris, Stephanie
    Yardim, Yavuz
    le Jeune, Alexandre
    Sarakbi, Ahmad
    Mertens, Dominique
    Kauffmann, Jean-Michel
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 102 : 267 - 275
  • [26] Shipboard Flow-Through Complex for Measuring Bio-Optical and Hydrological Seawater Characteristics
    Goldin, Yu A.
    Glukhovets, D., I
    Gureev, B. A.
    Grigoriev, A., V
    Artemiev, V. A.
    OCEANOLOGY, 2020, 60 (05) : 713 - 720
  • [27] FLOW-THROUGH BIOSENSOR FOR SEQUENTIAL DETERMINATION OF TOTAL AND PROSTATIC ACID-PHOSPHATASE-ACTIVITY
    SANCHEZCABEZUDO, M
    FERNANDEZROMERO, JM
    DECASTRO, MDL
    SENSORS AND ACTUATORS B-CHEMICAL, 1995, 23 (01) : 9 - 15
  • [28] The architecture and metabolic traits of monospecific photosynthetic biofilms studied in a custom flow-through system
    Fanesi, Andrea
    Martin, Thierry
    Breton, Cyril
    Bernard, Olivier
    Briandet, Romain
    Lopes, Filipa
    BIOTECHNOLOGY AND BIOENGINEERING, 2022, 119 (09) : 2459 - 2470
  • [29] Shipboard Flow-Through Complex for Measuring Bio-Optical and Hydrological Seawater Characteristics
    Yu. A. Goldin
    D. I. Glukhovets
    B. A. Gureev
    A. V. Grigoriev
    V. A. Artemiev
    Oceanology, 2020, 60 : 713 - 720
  • [30] Whole-cell luminescence-based flow-through biodetector for toxicity testing
    Philipp Stolper
    Susanne Fabel
    Michael G. Weller
    Dietmar Knopp
    Reinhard Niessner
    Analytical and Bioanalytical Chemistry, 2008, 390 : 1181 - 1187
12345