Comparison of Illumination Methods for Flow-Through Optofluidic Biosensors

被引：0
|
作者：
Hamblin, Matthew [1 ]
Wright, Joel [1 ]
Schmidt, Holger [2 ]
Hawkins, Aaron R. [1 ]
机构：
[1] Brigham Young Univ, Elect & Comp Engn, 450 Engn Bldg, Provo, UT 84602 USA
[2] Univ Calif Santa Cruz, Elect & Comp Engn, 1156 High St, Santa Cruz, CA 95064 USA
来源：
MICROMACHINES | 2023年 / 14卷 / 04期
关键词：
optofluidic; lab-on-a-chip; fluorescence; biosensor;
D O I：
10.3390/mi14040723
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Optofluidic biosensors have become an important medical diagnostic tool because they allow for rapid, high-sensitivity testing of small samples compared to standard lab testing. For these devices, the practicality of use in a medical setting depends heavily on both the sensitivity of the device and the ease of alignment of passive chips to a light source. This paper uses a model previously validated by comparison to physical devices to compare alignment, power loss, and signal quality for windowed, laser line, and laser spot methods of top-down illumination.
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页数：14
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