Breakthrough of glycobiology in the 21st century

被引：7
|
作者：
Mahara, Gehendra [1 ,2 ]
Tian, Cuihong [1 ,2 ,3 ]
Xu, Xiaojia [1 ,3 ,4 ]
Zhu, Jinxiu [5 ,6 ]
机构：
[1] First Affiliated Hosp Shantou Univ Med Coll, Clin Res Ctr, Shantou, Guangdong, Peoples R China
[2] First Affiliated Hosp Shantou Univ Med Coll, Dept Cardiovasc Med, Shantou, Guangdong, Peoples R China
[3] Edith Cowan Univ, Ctr Precis Hlth, Perth, WA, Australia
[4] First Affiliated Hosp Shantou Univ Med Coll, Dept Infect Control, Shantou, Guangdong, Peoples R China
[5] First Affiliated Hosp Shantou Univ Med Coll, Inst Clin Electrocardiog, Shantou, Guangdong, Peoples R China
[6] Shantou Univ Med Coll, Longgang Matern & Child Inst, Shenzhen, Guangdong, Peoples R China
来源：
FRONTIERS IN IMMUNOLOGY | 2023年 / 13卷
基金：
中国国家自然科学基金;
关键词：
glycobiology; glycan; carbohydrate; nanotechnology; drug development; vaccine; GLYCOSYLATION; GLYCANS; GLYCOPROTEOMICS; GLYCOMICS;
D O I：
10.3389/fimmu.2022.1071360
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
As modern medicine began to emerge at the turn of the 20th century, glycan-based therapies advanced. DNA- and protein-centered therapies became widely available. The research and development of structurally defined carbohydrates have led to new tools and methods that have sparked interest in the therapeutic applications of glycans. One of the latest omics disciplines to emerge in the contemporary post-genomics age is glycomics. In addition, to providing hope for patients and people with different health conditions through a deeper understanding of the mechanisms of common complex diseases, this new specialty in system sciences has much to offer to communities involved in the development of diagnostics and therapeutics in medicine and life sciences.This review focuses on recent developments that have pushed glycan-based therapies into the spotlight in medicine and the technologies powering these initiatives, which we can take as the most significant success of the 21st century.
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页数：5
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