Recent Advances in the Development of Drug Delivery Applications of Magnetic Nanomaterials

被引:30
|
作者
Pusta, Alexandra [1 ,2 ]
Tertis, Mihaela [1 ]
Craciunescu, Izabell [3 ]
Turcu, Rodica [3 ]
Mirel, Simona [2 ]
Cristea, Cecilia [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Dept Analyt Chem & Instrumental Anal, 4 Louis Pasteur St, Cluj Napoca 400349, Romania
[2] Iuliu Hatieganu Univ Med & Pharm, Dept Med Devices, 4 Pasteur St, Cluj Napoca 400349, Romania
[3] Natl Inst Res & Dev Isotop & Mol Technol, Cluj Napoca 400293, Romania
关键词
magnetic nanomaterials; cancer; drug delivery systems; targeted therapy; personalized treatment; IRON-OXIDE NANOPARTICLES; CORE-SHELL NANOPARTICLES; IN-VITRO EVALUATION; SURFACE MODIFICATION; COLLOIDAL SPHERES; ANTICANCER DRUG; CANCER CELLS; MICRO-RNA; PARTICLES; CLUSTERS;
D O I
10.3390/pharmaceutics15071872
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
With the predicted rise in the incidence of cancer, there is an ever-growing need for new cancer treatment strategies. Recently, magnetic nanoparticles have stood out as promising nanostructures for imaging and drug delivery systems as they possess unique properties. Moreover, magnetic nanomaterials functionalized with other compounds can lead to multicomponent nanoparticles with innovative structures and synergetic performance. The incorporation of chemotherapeutic drugs or RNA in magnetic drug delivery systems represents a promising alternative that can increase efficiency and reduce the side effects of anticancer therapy. This review presents a critical overview of the recent literature concerning the advancements in the field of magnetic nanoparticles used in drug delivery, with a focus on their classification, characteristics, synthesis and functionalization methods, limitations, and examples of magnetic drug delivery systems incorporating chemotherapeutics or RNA.
引用
收藏
页数:37
相关论文
共 50 条
  • [31] Peptide Nanomaterials for Drug Delivery Applications
    Pentlavalli, Sreekanth
    Coulter, Sophie
    Laverty, Garry
    CURRENT PROTEIN & PEPTIDE SCIENCE, 2020, 21 (04) : 401 - 412
  • [32] Recent Advances on the Design and Applications of Antimicrobial Nanomaterials
    Ortega-Nieto, Clara
    Losada-Garcia, Noelia
    Prodan, Doina
    Furtos, Gabriel
    Palomo, Jose M.
    NANOMATERIALS, 2023, 13 (17)
  • [33] Recent advances in applications of nanomaterials for sample preparation
    Xu, Linnan
    Qi, Xiaoyue
    Li, Xianjiang
    Bai, Yu
    Liu, Huwei
    TALANTA, 2016, 146 : 714 - 726
  • [34] Recent Advances in Theranostic Applications of Nanomaterials in Cancer
    Ahmed, Faraha
    Khan, Mohammad Ahmed
    Haider, Nafis
    Ahmad, Mohammad Zaki
    Ahmad, Javed
    CURRENT PHARMACEUTICAL DESIGN, 2022, 28 (02) : 133 - 150
  • [35] Recent Advances in Nanomaterials for Dermal and Transdermal Applications
    Zoabi, Amani
    Touitou, Elka
    Margulis, Katherine
    COLLOIDS AND INTERFACES, 2021, 5 (01)
  • [36] Electrospun Nanomaterials for Energy Applications: Recent Advances
    Santangelo, Saveria
    APPLIED SCIENCES-BASEL, 2019, 9 (06):
  • [37] Recent Advances in Biomedical Applications of Biogenic Nanomaterials
    Bhagat, Devidas S.
    Gurnule, Wasudeo B.
    Bumbrah, Gurvinder S.
    Koinkar, Pankaj
    Chawla, Pooja A.
    CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2023, 24 (01) : 86 - 100
  • [38] Recent Advances in Perovskite Nanomaterials for Sensing Applications
    Dabas, Samiksha
    Kumar, Manish
    Singh, Dharm Veer
    Kumar, Prashant
    Dwivedi, D. K.
    Srivastava, Abhay Nanda
    JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 2024, 171 (11)
  • [39] Recent advances in photothermal nanomaterials for ophthalmic applications
    Zhuang, Jiayuan
    Jia, Linhui
    Li, Chenghao
    Yang, Rui
    Wang, Jiapeng
    Wang, Wen-an
    Zhou, Heng
    Luo, Xiangxia
    BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 2025, 16 : 195 - 215
  • [40] Recent Advances of Amorphous Nanomaterials: Synthesis and Applications
    Li, Lidong
    Zhao, Hewei
    Wang, Xiaotian
    Guo, Lin
    CHINESE JOURNAL OF CHEMISTRY, 2024, 42 (22) : 2853 - 2876