Recent Advances in the Development of Drug Delivery Applications of Magnetic Nanomaterials

被引:30
|
作者
Pusta, Alexandra [1 ,2 ]
Tertis, Mihaela [1 ]
Craciunescu, Izabell [3 ]
Turcu, Rodica [3 ]
Mirel, Simona [2 ]
Cristea, Cecilia [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Dept Analyt Chem & Instrumental Anal, 4 Louis Pasteur St, Cluj Napoca 400349, Romania
[2] Iuliu Hatieganu Univ Med & Pharm, Dept Med Devices, 4 Pasteur St, Cluj Napoca 400349, Romania
[3] Natl Inst Res & Dev Isotop & Mol Technol, Cluj Napoca 400293, Romania
关键词
magnetic nanomaterials; cancer; drug delivery systems; targeted therapy; personalized treatment; IRON-OXIDE NANOPARTICLES; CORE-SHELL NANOPARTICLES; IN-VITRO EVALUATION; SURFACE MODIFICATION; COLLOIDAL SPHERES; ANTICANCER DRUG; CANCER CELLS; MICRO-RNA; PARTICLES; CLUSTERS;
D O I
10.3390/pharmaceutics15071872
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
With the predicted rise in the incidence of cancer, there is an ever-growing need for new cancer treatment strategies. Recently, magnetic nanoparticles have stood out as promising nanostructures for imaging and drug delivery systems as they possess unique properties. Moreover, magnetic nanomaterials functionalized with other compounds can lead to multicomponent nanoparticles with innovative structures and synergetic performance. The incorporation of chemotherapeutic drugs or RNA in magnetic drug delivery systems represents a promising alternative that can increase efficiency and reduce the side effects of anticancer therapy. This review presents a critical overview of the recent literature concerning the advancements in the field of magnetic nanoparticles used in drug delivery, with a focus on their classification, characteristics, synthesis and functionalization methods, limitations, and examples of magnetic drug delivery systems incorporating chemotherapeutics or RNA.
引用
收藏
页数:37
相关论文
共 50 条
  • [21] Recent advances of microneedles for biomedical applications: drug delivery and beyond
    Jian Yang
    Xinli Liu
    Yunzhi Fu
    Yujun Song
    Acta Pharmaceutica Sinica B, 2019, 9 (03) : 469 - 483
  • [22] Recent advances in microneedle designs and their applications in drug and cosmeceutical delivery
    Parhi, Rabinarayan
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 75
  • [23] Recent advances of microneedles for biomedical applications: drug delivery and beyond
    Yang, Jian
    Liu, Xinli
    Fu, Yunzhi
    Song, Yujun
    ACTA PHARMACEUTICA SINICA B, 2019, 9 (03) : 469 - 483
  • [24] Recent advances in polymeric hydrogel nanoarchitectures for drug delivery applications
    Idumah, Christopher Igwe
    Nwuzor, I. C.
    Odera, S. R.
    Timothy, U. J.
    Ngenegbo, U.
    Tanjung, F. A.
    INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2024, 73 (01) : 1 - 32
  • [25] Engineering Strategies for Drug Delivery Recent Advances in the Development of Drug Delivery Systems and Devices
    Wang, Yong
    IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 2009, 28 (01): : 10 - 11
  • [26] Recent Advances in Drug Delivery
    Salem, Aliasger K.
    AAPS JOURNAL, 2024, 26 (03):
  • [27] Recent advances in porous nanomaterials-based drug delivery systems for cancer immunotherapy
    Li, Su-Ran
    Huo, Fang-Yi
    Wang, Han-Qi
    Wang, Jing
    Xu, Chun
    Liu, Bing
    Bu, Lin-Lin
    JOURNAL OF NANOBIOTECHNOLOGY, 2022, 20 (01)
  • [28] Recent advances in nanoarchitectonics of two-dimensional nanomaterials for dental biosensing and drug delivery
    Cui, Di
    Kong, Na
    Yang, Wenrong
    Yan, Fuhua
    ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2025, 337
  • [29] Recent Advances in Poly(α-L-glutamic acid)-Based Nanomaterials for Drug Delivery
    Zhang, Yu
    Song, Wenliang
    Lu, Yiming
    Xu, Yixin
    Wang, Changping
    Yu, Deng-Guang
    Kim, Il
    BIOMOLECULES, 2022, 12 (05)
  • [30] Recent advances in porous nanomaterials-based drug delivery systems for cancer immunotherapy
    Su-Ran Li
    Fang-Yi Huo
    Han-Qi Wang
    Jing Wang
    Chun Xu
    Bing Liu
    Lin-Lin Bu
    Journal of Nanobiotechnology, 20