Synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes by cross-coupling induced by transition metals - formation of C-C bonds

被引：4

作者：

Yasukawa, Tomohiro ^{[1
]}

Haheim, Katja S. ^{[1
]}

Cossy, Janine ^{[1
]}

机构：

[1] PSL, ESPCI Paris, Mol Macromol Chem & Mat, CNRS, F-75005 Paris, France

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 38期

关键词：

LIQUID-CRYSTALLINE; BRIDGEHEAD; ROUTE; ARYL; SALTS; SCOPE;

D O I：

10.1039/d3ob01036h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes (BCPs), by forming a C-C bond, can be achieved by cross-coupling reactions using transition metal catalysts. Two main strategies are described to access these 1,3-disubstituted BCPs, either from nucleophilic BCPs or electrophilic BCPs. Mechanisms are included where relevant. The synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes (BCPs), by forming a C-C bond, can be achieved by cross-coupling reaction using transition metal catalysts.

引用

页码：7666 / 7680

页数：15

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