Oral and nasal vaccination: current prospects, challenges, and impact of nanotechnology-based delivery systems

被引：1
|
作者：
Paiva, Natalia Floriano [1 ]
Vicentini, Fabiana Testa Moura de Carvalho [1 ,2 ]
机构：
[1] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Sao Paulo, Brazil
[2] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Av Cafe S-N,Monte Alegre, BR-14040903 Ribeirao Preto, SP, Brazil
来源：
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2023年 / 59卷
基金：
巴西圣保罗研究基金会;
关键词：
Mucosal vaccination; Oral vaccine; Nasal vaccine; Nanocarriers; Nano-vaccinology; MESSENGER-RNA VACCINES; INTRANASAL DELIVERY; NANOPARTICLES; STRATEGIES; CARRIERS; DESIGN;
D O I：
10.1590/s2175-97902023e21769
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Currently, mucosal vaccine administration has stood out as an easier and non-invasive application method. It can also be used to induce local and systemic immune responses. In the COVID-19 pandemic context, nasal and oral vaccines have been developed based on different technological platforms. This review addressed relevant aspects of mucosal vaccine administration, with emphasis on oral and nasal vaccinations, in addition to the importance of using nanotechnology-based delivery systems to enable these strategies.
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页数：16
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