Proton versus photon radiation therapy: A clinical review

被引：36
|
作者：
Chen, Zhe [1 ]
Dominello, Michael M. M. [2 ]
Joiner, Michael C. C. [2 ]
Burmeister, Jay W. W. [2 ]
机构：
[1] Wayne State Univ, Sch Med, Detroit, MI 48202 USA
[2] Wayne State Univ, Karmanos Canc Inst, Sch Med, Dept Oncol, Detroit, MI USA
来源：
FRONTIERS IN ONCOLOGY | 2023年 / 13卷
关键词：
proton radiation therapy; proton radiotherapy; proton therapy clinical trials; proton therapy non-randomized study; proton therapy randomized study; INTENSITY-MODULATED RADIOTHERAPY; CELL LUNG-CANCER; QUALITY-OF-LIFE; BEAM THERAPY; CRANIOSPINAL IRRADIATION; PROSTATE-CANCER; MULTIINSTITUTIONAL ANALYSIS; DISEASE-CONTROL; OUTCOMES; TOXICITY;
D O I：
10.3389/fonc.2023.1133909
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
While proton radiation therapy offers substantially better dose distribution characteristics than photon radiation therapy in certain clinical applications, data demonstrating a quantifiable clinical advantage is still needed for many treatment sites. Unfortunately, the number of patients treated with proton radiation therapy is still comparatively small, in some part due to the lack of evidence of clear benefits over lower-cost photon-based treatments. This review is designed to present the comparative clinical outcomes between proton and photon therapies, and to provide an overview of the current state of knowledge regarding the effectiveness of proton radiation therapy.
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页数：28
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