New Derivatives From 4-Amino Anti-Pyrine And Vanillin, Synthesis Characterization And Antibacterial Activity

被引:3
作者
Alabidi, Hawraa M. [1 ]
Farhan, Ali M. [2 ]
Al-labban, Hutham Mahmood Yousif [1 ]
Aljanaby, Ahmed Abduljabbar Jaloob [3 ]
机构
[1] Univ Kufa, Fac Sci, Dept Chem, Kufa, Iraq
[2] Minist Educ, Al Najaf, Iraq
[3] Univ Kufa, Fac Sci, Dept Biol, Kufa, Iraq
来源
EGYPTIAN JOURNAL OF CHEMISTRY | 2023年 / 66卷 / 01期
关键词
4-Amino antipyrine; Azo schiff base; Complexes; Biological activity; S; aureus; P; aeruginosa; COMPLEXES;
D O I
10.21608/EJCHEM.2022.135727.5977
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Schiff base, Azo-Schiff base, nickel (II), and copper (II) complexes have been prepared successfully from 4-amino antipyrine and vanillin and diagnosed by UV-visible, FT-IR, 1H-NMR, and 13C-NMR. The derivative compound Azo-Schiff with a 200 mg/ml concentration has good antibacterial activity with a diameter of inhibition zone 16.11 +/- 0.1035 mm and 13.21 +/- 0.4044 against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively. Therefore, this compound may be considered a raw material for manufacturing treatments against these bacterial infections.
引用
收藏
页码:175 / 181
页数:7
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