New Derivatives From 4-Amino Anti-Pyrine And Vanillin, Synthesis Characterization And Antibacterial Activity

被引：3

作者：

Alabidi, Hawraa M. ^{[1
]}

Farhan, Ali M. ^{[2
]}

Al-labban, Hutham Mahmood Yousif ^{[1
]}

Aljanaby, Ahmed Abduljabbar Jaloob ^{[3
]}

机构：

[1] Univ Kufa, Fac Sci, Dept Chem, Kufa, Iraq

[2] Minist Educ, Al Najaf, Iraq

[3] Univ Kufa, Fac Sci, Dept Biol, Kufa, Iraq

来源：

EGYPTIAN JOURNAL OF CHEMISTRY | 2023年 / 66卷 / 01期

关键词：

4-Amino antipyrine; Azo schiff base; Complexes; Biological activity; S; aureus; P; aeruginosa; COMPLEXES;

D O I：

10.21608/EJCHEM.2022.135727.5977

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Schiff base, Azo-Schiff base, nickel (II), and copper (II) complexes have been prepared successfully from 4-amino antipyrine and vanillin and diagnosed by UV-visible, FT-IR, 1H-NMR, and 13C-NMR. The derivative compound Azo-Schiff with a 200 mg/ml concentration has good antibacterial activity with a diameter of inhibition zone 16.11 +/- 0.1035 mm and 13.21 +/- 0.4044 against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively. Therefore, this compound may be considered a raw material for manufacturing treatments against these bacterial infections.

引用

页码：175 / 181

页数：7

共 30 条

[1] A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study [J].

Abdul-Rida, Nabeel A. ;

Farhan, Ali M. ;

Al-Masoudi, Najim A. ;

Saeed, Bahjat A. ;

Miller, Dannah ;

Lin, Ming-Fong .

MOLECULAR DIVERSITY, 2021, 25 (02) :661-671

[2] Spectral and thermal investigation of novel biologically active (N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl-amino)-2-oxo-cetimidic acid) ligand and its metal complexes [J].

AbouEl-Enein, Saeyda A. ;

Emam, Sanaa M. ;

Wagdy, Reham M. ;

Abouzayed, Fatma, I .

JOURNAL OF MOLECULAR STRUCTURE, 2020, 1215

[3]

Adam R.W., 2019, Nano Biomed Eng., V11, P99, DOI [10.5101/nbe.v11i2.p99-110, DOI 10.5101/NBE.V11I2.P99-110]

[4] Synthesis and investigation of thermal properties of vanadyl complexes with azo-containing Schiff-base dyes [J].

Al-Hamdani, Abbas Ali Salih ;

Balkhi, Abdel Majid ;

Falah, A. ;

Shaker, Shayma A. .

JOURNAL OF SAUDI CHEMICAL SOCIETY, 2016, 20 (05) :487-501

[5]

Al-labban H., 2020, INT J PHARM RES, V1, P2394

[6] Evaluation of Galectin-3 and CD19 in Helicobacter pylori patients infected with stomach cancer [J].

Alhasnawi, Haneen Mohammed Reda Jaber ;

Aljanaby, Ahmed Abduljabbar Jaloob .

GENE REPORTS, 2022, 26

[7]

Aljanaby A., 2017, Res J Pharm Technol, V10, P3264, DOI [10.5958/0974-360X.2017.00579.0, DOI 10.5958/0974-360X.2017.00579.0]

[8]

Aljanaby A.A.J., 2022, GENE REP

[9] Antibacterial activity of an aqueous extracts of Alkanna tinctoria roots against drug resistant aerobic pathogenic bacteria isolated from patients with burns infections [J].

Aljanaby, Ahmed Abduljabbar Jaloob .

RUSSIAN OPEN MEDICAL JOURNAL, 2018, 7 (01)

[10]

Anitha C., 2011, International Journal of Inorganic Chemistry, V2011, DOI [https://doi.org/10.1155/2011/493942, DOI 10.1155/2011/493942, 10.1155/2011/493942]

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