Clinical and Endoscopic Differences Between Patients With Barrett's Esophagus With and Without Dysplasia/Adenocarcinoma

被引：0

作者：

Valdovinos-Andraca, Francisco ^{[1
]}

Bartnicki-Navarrete, Isaac ^{[1
]}

Bernal-Mendez, Ambrosio R. ^{[1
]}

Barreto-Zuniga, Rafael Rafael ^{[1
]}

Romano-Munive, Adriana F. ^{[1
]}

Gamboa-Dominguez, Armando ^{[2
]}

Elizondo-Rivera, Javier ^{[1
]}

Briseno-Garcia, Daniel ^{[1
]}

Tellez-Avila, Felix I. ^{[3
]}

机构：

[1] Natl Inst Med Sci & Nutr Salvador Zubiran, Endoscopy, Mexico City, DF, Mexico

[2] Natl Inst Med Sci & Nutr Salvador Zubiran, Pathol, Mexico City, DF, Mexico

[3] Univ Arkansas Med Sci, Gastroenterol & Hepatol, Little Rock, AR 72205 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 10期

关键词：

barrett's esophagus; mexico; risk factors; esophageal adenocarcinoma; dysplasia; LOW-GRADE DYSPLASIA; RISK-FACTORS; MANAGEMENT; DIAGNOSIS; ADENOCARCINOMA; MORTALITY; SIZE;

D O I：

10.7759/cureus.46323

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Barrett's esophagus (BE) is the main precursor of esophageal adenocarcinoma (EAC). This study aimed to identify the risk factors associated with BE progression to dysplasia or EAC in a Latin population.Methods: The study is a retrospective analysis of a single-center cohort of patients with BE, evaluated from 2002 to 2012.Results: We identified 420 patients with BE; 281 (66.9%) of them were men with a mean age of 57.2 +/- 15.3 years. Among all BE patients evaluated, 81 (19.3%) had progression to some degree of dysplasia/EAC. The mean follow-up was 5.6 years. Multivariate analysis showed that age (OR = 1.03), cigarette smoking (OR = 3.05), long-segment BE (OR = 4.81), and a visible lesion on BE (OR = 6.94) were associated with progression to dysplasia/EAC. Conclusion: In Latin patients with BE, age, cigarette smoking, long-segment BE, and the presence of lesions were associated with the presence of dysplasia/EAC.

引用

页数：6

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