Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis

被引：0

作者：

Hou, Wenjie ^{[1
]}

Tu, Yifan ^{[2
]}

Zheng, Minghua ^{[3
]}

Zeng, Qiqiang ^{[4
]}

机构：

[1] Wenzhou Heping Int Hosp, Radiol Dept, Wenzhou 325000, Zhejiang, Peoples R China

[2] Wenzhou Med Univ, Clin Med Coll 1, Wenzhou 325000, Zhejiang, Peoples R China

[3] First Affiliated Hosp Wenzhou, Dept Infect & Liver Dis, Liver Res Ctr, Wenzhou 325000, Zhejiang, Peoples R China

[4] Wenzhou Heping Int Hosp, Dept Gen Surg, Wenzhou 325000, Zhejiang, Peoples R China

来源：

HEPATOMA RESEARCH | 2023年 / 9卷

关键词：

Intrahepatic cholangiocarcinoma; heterogeneity; etiology; intrahepatic lithiasis; early diagnosis; treatment; prognosis; PROGNOSIS; RESECTION; RECURRENCE; ETIOLOGY;

D O I：

10.20517/2394-5079.2023.40

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The heterogeneity of tumors results in significantly distinct biological characteristics of intrahepatic cholangiocarcinoma (ICC) caused by different etiologies. Among them, ICC caused by intrahepatic lithiasis (IHL-ICC) presents challenges in early detection, tumor staging, and surgical treatment, and has the poorest prognosis among all etiologies of ICC patients. Thus, it is essential to focus on early assessment of the possibility of developing ICC, prompt intervention of intrahepatic lithiasis, anatomical resection of hepatic parenchyma corresponding to the branch of the intrahepatic bile duct undergoing cancerous transformation, and enhanced postoperative follow-up of hepatolithiasis and ICC for IHL-ICC patients. These interventions are crucial to improve the clinical outcomes and overall survival of IHL-ICC patients.

引用

页数：5

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