Component composition of essential oil of Rhodiola algida (Ledeb.) Fisch & C.A. Mey and its biological activity

被引:0
作者
Zhumagul, M. Zh. [1 ,2 ]
Kubentayev, S. A. [2 ]
Kurmanbayeva, M. S. [3 ]
Myrzagaliyeva, A. B. [1 ]
Suleimen, R. N. [4 ]
Suleimen, Ye. M. [5 ,6 ]
Samarkhanova, D. [7 ]
机构
[1] Astana Int Univ, Astana, Kazakhstan
[2] Inst Bot & Phytoinroduct, Astana Bot Garden, Astana, Kazakhstan
[3] Al Farabi Kazakh Natl Univ, Alma Ata, Kazakhstan
[4] Eurasian Natl Univ, Astana, Kazakhstan
[5] Kazakh Univ Technol & Business, Astana, Kazakhstan
[6] Sh Ualikhanov Kokshetau Univ, Kokshetau, Kazakhstan
[7] Nazarbayev Univ, Astana, Kazakhstan
来源
INTERNATIONAL JOURNAL OF BIOLOGY AND CHEMISTRY | 2023年 / 16卷 / 01期
关键词
Key words; Rhodiola algida; essential oils; components; antioxidant activity; DOUBLE-BLIND; ROSEA; EXTRACT; SHR-5; CRENULATA; PHEROMONE; CAPACITY; PLACEBO; FATIGUE; STRESS;
D O I
10.26577/ijbch.2023.v16.i1.012
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
For the first time the component composition of essential oil of Rhodiola algida (Ledeb.) Fisch & C.A. Mey. family Crassulaceae, collected in places of natural growth in July 2020 in the Kazakh Altai was studied. The component composition of essential oil of this species was determined by gas chromatography and chromatography-mass spectrometry. The method of chromatography-mass spectrometry detected 100 components, of which 79 substances were identified, accounting for 82-83% of the total essential oil. Antioxidant activity was determined by the FRAP method. R. algida essential oil showed low antioxidant activity compared with butyl hydroxyanisole (BHA) at concentrations of 0.25-1.0 mg/ml, confirming the antioxidant properties of R. algida. Based on the results of cytotoxic activity against Artemia salina L. larvae, it was concluded that R. algida essential oil has good lethal toxicity at all concentrations tested, which proves the cytotoxicity of R. algida. At present, studies of R. algida based on substances from this plant and methods of their analysis are of direct interest for phytopreparation.
引用
收藏
页码:113 / 127
页数:15
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