Prospective features of functional 2D nanomaterial graphene oxide in the wound healing process

被引:22
作者
Chandrasekaran, Rajkuberan [1 ]
Krishnan, Muthukumar [2 ]
Bupesh, Giridharan [3 ]
Chacko, Sonu [1 ]
Gawade, Omkar [1 ]
Hasan, Sheik [1 ]
George, Evelin [4 ]
Vijayakumar, Tharumasivam Siva [5 ]
Sundaram, Meenakshi [6 ]
Sagadevan, Suresh [7 ]
机构
[1] Karpagam Acad Higher Educ, Dept Biotechnol, Coimbatore, India
[2] Anna Univ, Dept Petrochem Technol, Tiruchirappalli, India
[3] Nagaland Univ, Dept Forestry, Nat Prod & Tribal Hlth Res, Lumami 798627, Nagaland, India
[4] JSS Acad Higher Educ, Sch Life Sci, Dept Biochem, Ooty Campus, Ooty, India
[5] Srimad Andavan Arts & Sci Coll, PG & Res Dept Biotechnol, Tiruchirappalli, India
[6] Saveetha Inst Med & Tech Sci, Dept Anat, Chennai, India
[7] Univ Malaya, Nanotechnol & Catalysis Res Ctr, Kuala Lumpur 50603, Malaysia
关键词
Graphene; Graphene oxide; Wound; Nanomaterials; IN-VIVO; SILVER NANOPARTICLES; DRUG-DELIVERY; STEM-CELLS; ACID; ANTIBACTERIAL; GRAPHITE; CARE; COMBINATION; COMPOSITES;
D O I
10.1016/j.jddst.2023.104352
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The treatment of chronic and non-chronic wounds is becoming a major challenge for clinicians due to various intrinsic and extrinsic factors. Therefore, a newly formulated technology should be introduced into the treatment process to substantiate efficacy and efficiency. Nanotechnology-based wound care materials are getting awesome responses from medical research fraternities owing to their unique physic-chemical properties and pose precise targeting of wound infection at various stages in the healing process. Among the nanomaterials, Graphene Oxide (GO) carbon allotrope is intensively used in various wound healing applications. These oxide nanomaterials are biocompatible, biodegradable, easily functionalized with drugs, have surface modification and charge, and are rapidly internalized in the cell membrane. These qualitative properties merit the use of GO in treating chronic and non-chronic wounds. Therefore, the present review emphasizes the role of Graphene oxide in the wound healing process and explains its molecular dynamics in the healing process.
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页数:15
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