Vibrio species as next-generation chassis for accelerated synthetic biology

被引：4

作者：

Hong, Changhwan ^{[1
]}

Kim, Yoojin ^{[2
]}

Lee, Hyunjin ^{[1
,3
]}

Yun, Saebom ^{[1
]}

Lim, Hyun Gyu ^{[4
]}

Yang, Jina ^{[5
]}

Jang, Sungho ^{[1
,2
,3
]}

机构：

[1] Incheon Natl Univ, Dept Bioengn & Nanobioengn, Incheon 22012, South Korea

[2] Incheon Natl Univ, Coll Life Sci & Bioengn, Div Bioengn, Incheon 22012, South Korea

[3] Incheon Natl Univ, Res Ctr Bio Mat & Proc Dev, Incheon 22012, South Korea

[4] Inha Univ, Dept Biol Engn, Incheon 22122, South Korea

[5] Jeju Natl Univ, Dept Chem Engn, Jeju 63243, South Korea

来源：

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | 2024年 / 29卷 / 02期

关键词：

Vibrio natriegens; Vibrio species; Chassis strain; Design-build-test-learn cycle; Synthetic biology; Metabolic engineering; NATURAL TRANSFORMATION MUGENT; ESCHERICHIA-COLI; NATRIEGENS; DESIGN; HOST;

D O I：

10.1007/s12257-024-00023-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Synthetic biology aims to establish engineering principles for biological systems by leveraging the design-build-test-learn (DBTL) cycle. Central to the success of the DBTL cycle is the selection of a suitable chassis, which is the environment in which biological designs are tested. Every step of this cycle is strongly influenced by the properties of chassis. A successful chassis must meet various criteria, prompting ongoing research regarding new candidates. Recently, species within the Vibrio genus, notably Vibrio natriegens and related strains, have emerged as promising next-generation chassis due to their rapid growth rates, versatile substrate utilization, and biosafety level 1 classification. These properties make them highly attractive for accelerating the DBTL cycle with the potential for efficient protein and metabolite production. This review emphasizes the foundational requirements for efficient engineering in synthetic biology, including genetic parts, vectors, and genome engineering technologies tailored to Vibrio species. Practical applications, such as metabolic engineering and protein expression, have been discussed, offering a comprehensive summary of recent advances. This paper also outlines the future directions and suggestions for fully unlocking the potential of Vibrio species as next-generation chassis.

引用

页码：241 / 253

页数：13

共 59 条

[11] PSEUDOMONAS-NATRIEGENS, A MARINE BACTERIUM WITH A GENERATION TIME OF LESS THAN 10 MINUTES [J].

EAGON, RG .

JOURNAL OF BACTERIOLOGY, 1962, 83 (04) :736-&

[12] Selection of High Producers From Combinatorial Libraries for the Production of Recombinant Proteins in Escherichia coli and Vibrio natriegens [J].

Eichmann, Joel ;

Oberpaul, Markus ;

Weidner, Tobias ;

Gerlach, Doreen ;

Czermak, Peter .

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2019, 7

[13] Exploiting the Feedstock Flexibility of the Emergent Synthetic Biology Chassis Vibrio natriegens for Engineered Natural Product Production [J].

Ellis, Gregory A. ;

Tschirhart, Tanya ;

Spangler, Joseph ;

Walper, Scott A. ;

Medintz, Igor L. ;

Vora, Gary J. .

MARINE DRUGS, 2019, 17 (12)

[14] High rate 2,3-butanediol production with Vibrio natriegens [J].

Erian A.M. ;

Freitag P. ;

Gibisch M. ;

Pflügl S. .

Bioresource Technology Reports, 2020, 10

[15] The inorganic ion content of native aquatic bacteria [J].

Fagerbakke, KM ;

Norland, S ;

Heldal, M .

CANADIAN JOURNAL OF MICROBIOLOGY, 1999, 45 (04) :304-311

[16] Bacterial Genetic Engineering by Means of Recombineering for Reverse Genetics [J].

Fels, Ursula ;

Gevaert, Kris ;

Van Damme, Petra .

FRONTIERS IN MICROBIOLOGY, 2020, 11

[17] Speeding up bioproduction of selenium nanoparticles by using Vibrio natriegens as microbial factory [J].

Fernandez-Llamosas, Helga ;

Castro, Laura ;

Blazquez, Maria Luisa ;

Diaz, Eduardo ;

Carmona, Manuel .

SCIENTIFIC REPORTS, 2017, 7

[18] STUDIES ON TRANSFORMATION OF ESCHERICHIA-COLI WITH PLASMIDS [J].

HANAHAN, D .

JOURNAL OF MOLECULAR BIOLOGY, 1983, 166 (04) :557-580

[19] Vibrio natriegens: an ultrafast-growing marine bacterium as emerging synthetic biology chassis [J].

Hoff, Josef ;

Daniel, Benjamin ;

Stukenberg, Daniel ;

Thuronyi, B. W. ;

Waldminghaus, Torsten ;

Fritz, Georg .

ENVIRONMENTAL MICROBIOLOGY, 2020, 22 (10) :4394-4408

[20] Establishment of a salt-induced bioremediation platform from marine Vibrio natriegens [J].

Huang, Ling ;

Ni, Jun ;

Zhong, Chao ;

Xu, Ping ;

Dai, Junbiao ;

Tang, Hongzhi .

COMMUNICATIONS BIOLOGY, 2022, 5 (01)

← 1 2 3 4 5 6 →