Synthesis and Characterization of Benzimidazole Derivatives and Evaluation of Antimicrobial activity

被引:0
作者
Vyas, Kamal Kant [1 ]
Rajpurohit, Sangeeta [2 ]
Vaishnav, Yudhishthir [1 ]
机构
[1] JNVU Jodhpur, Dept Chem, Jodhpur 342001, Rajasthan, India
[2] Lachoo Mem Coll, Organ Iab, Jodhpur 342001, Rajasthan, India
关键词
Benzimidazole; Antibacterial; Antifungal; ANTIBACTERIAL ACTIVITY;
D O I
10.13005/ojc/390424
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A series of benzimidazole derivatives were synthesized for this investigation. NMR and IR spectrum analysis as well as carbon, hydrogen, and nitrogen studies were used to characterize these novel synthesized derivatives. Antibacterial and antifungal tests were conducted on all of the newly synthesized compounds. Ciprofloxacin and fluconazole were utilized as reference medications in antibacterial and antifungal research, respectively. The microbiological assay revealed that the compounds show promising antibacterial and antifungal activity.
引用
收藏
页码:996 / 1001
页数:6
相关论文
共 19 条
  • [11] Khan SA, 1997, INDIAN J HETEROCY CH, V7, P55
  • [12] Synthesis and anti-bacterial activity of some novel 2-(6-fluorochroman-2-yl)-1-alkyl/acyl/aroyl-1H-benzimidazoles
    Kumar, Bobba Venkata Siva
    Vaidya, Sanjay Dashrath
    Kumar, Ramanatham Vinod
    Bhirud, Shekar Bhaskar
    Mane, Ramchandra Bhimrao
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 41 (05) : 599 - 604
  • [13] Synthesis, Characterization, and Biological Evaluation of Benzimidazole Derivatives as Potential Anxiolytics
    Nannapaneni, D. T.
    Atyam, Gupta V. S. S. S.
    Reddy, M., I
    Raidu, Sarva Ch
    [J]. JOURNAL OF YOUNG PHARMACISTS, 2010, 2 (03) : 273 - 279
  • [14] Sharma P, 1999, INDIAN J CHEM B, V38, P1289
  • [15] Shetgiri NP, 2001, INDIAN J CHEM B, V40, P163
  • [17] POSSIBLE ANTICONVULSANT THIAZOLO[3,2-A]BENZIMIDAZOLE MANNICH BASES .11.
    SINGH, JM
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (05) : 962 - &
  • [18] Taha Mamdouh A.M, 2005, J. Indian Chem. Soc., V82, P180
  • [19] Vostrova L.N., 1986, PHARM CHEM J+, V20, P404, DOI DOI 10.1007/BF00758335