Metformin : from public health issue to perioperative strategy

被引：1

作者：

Gricourt, Yann ^{[1
]}

Vialatte, Pierre-Baptiste ^{[1
]}

Avis, Geoffrey ^{[1
]}

Akkari, Zahir ^{[1
]}

Cuvillon, Philippe ^{[1
]}

机构：

[1] Univ Montpellier, Nimes Univ Hosp, Div Anesthesia Crit Care Pain & Emergency Med, UR UM103,IMAGINE, Pl Prof Debre, F-30000 Nimes, France

来源：

ANESTHESIE & REANIMATION | 2023年 / 9卷 / 03期

关键词：

Metformin; Surgery; Lactate; Glycemia; Benefit; Risk; LACTIC-ACIDOSIS; DIABETES-ASSOCIATION; HYPERGLYCEMIA; MANAGEMENT; RISK;

D O I：

10.1016/j.anrea.2023.06.001

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Metformin is the reference oral antidiabetic for the treatment of type 2 diabetes. Despite its many advantages (low cost, easy dosage and administration, few side effects, etc.), its use is the subject of debate, particularly in the perioperative context, due to the risk of lactic acidosis. The growing incidence of type 2 diabetes means that anaesthetists regularly manage patients on metformin. This review describes the public health issues associated with type 2 diabetes and metformin and summarizes the pharmacological properties of metformin. Next, metformin-related metabolic acidosis is detailed. Finally, we describe what anaesthetists need to know when managing patients treated with metformin.

引用

页码：258 / 267

页数：10

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