Worldwide prevalence and associated risk factors of obstructive sleep apnea: a meta-analysis and meta-regression

被引:46
作者
de Araujo Dantas, Anna Beatriz [1 ]
Goncalves, Flavio Magno [2 ,3 ]
Martins, Agnes Andrade [1 ,3 ]
Alves, Giorvan Aanderson [4 ]
Stechman-Neto, Jose [2 ,3 ]
Correa, Camila de Castro [3 ,5 ]
Santos, Rosane Sampaio [2 ,3 ]
Nascimento, Weslania Viviane [3 ,6 ]
de Araujo, Cristiano Miranda [2 ,3 ]
Meira Taveira, Karinna Verissimo [1 ,3 ]
机构
[1] Fed Univ Rio Grande Do Norte UFRN, Ctr Biosci, Dept Morphol, BR 101 Lagoa Nova, BR-59072970 Natal, RN, Brazil
[2] Tuiuti Univ Parana UTP, Curitiba, Brazil
[3] Ctr Adv Studies Systemat Review & Metaanal NARSM, Curitiba, Brazil
[4] Fed Univ Paraiba UFPB, Joao Pessoa, Brazil
[5] Planalto Univ Ctr Fed Dist UNIPLAN, Brasilia, Brazil
[6] Univ Autonoma Barcelona, Barcelona, Spain
关键词
Obstructive sleep apnea; Risk factors; Prevalence; Systematic review; MANDIBULAR ADVANCEMENT DEVICE; STOP-BANG QUESTIONNAIRE; GENDER-DIFFERENCES; CLINICAL-FEATURES; POPULATION; CHILDREN; POLYSOMNOGRAPHY; DIAGNOSIS; DISORDERS; COMMUNITY;
D O I
10.1007/s11325-023-02810-7
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
PurposeThis study aimed to identify the prevalence of obstructive sleep apnea (OSA) and associated risk factors globally.MethodsSix databases and registrations and three grey databases were explored for observational field research. Independently and impartially paired reviewers selected research, gathered data, and evaluated the methodological quality. Heterogeneity was investigated using subgroup analysis and meta-regression following the moderating variable in a meta-analysis of proportions with a random-effects model. The critical appraisal instrument developed by the Joanna Briggs Institute was used to evaluate the listed studies' methodology. The certainty of the evidence was evaluated using the GRADE tool.ResultsA total of 8236 articles were collected during the database search, resulting in 99 articles included for qualitative synthesis, and 98 articles were included for the meta-analysis. The estimated combined prevalence of OSA was 54% [CI 95% = 46-62%; I2 = 100%]. Mean age, percentage of moderate-severe cases, and the sample's body mass index (BMI) did not affect the heterogeneity that was already present when meta-regressed (p > 0.05). Ninety-one studies were deemed to have a low risk of bias, while eight were deemed to have a moderate risk. For OSA prevalence outcomes, the GRADE criteria were considered very low.ConclusionApproximately half of the people worldwide have OSA. High BMI, increasing age, and male gender are described as risk factors in the literature, but these covariates do not affect pre-existing heterogeneity.
引用
收藏
页码:2083 / 2109
页数:27
相关论文
共 125 条
[1]  
Abdel Dayem A, 2022, EGYPT J CHEST DIS TU, V71
[2]   Predictors of a Normal Sleep Study in Healthy Children with Sleep Disordered Breathing Symptoms [J].
Abraham, Elizabeth J. ;
Bains, Ashank ;
Rubin, Batsheva R. ;
Cohen, Michael B. ;
Levi, Jessica R. .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2021, 130 (09) :1029-1035
[3]  
Akkoyunlu ME, 2013, MULTIDISCIP RESP MED, P8
[4]  
Al-Abri Mohammed, 2011, Sultan Qaboos Univ Med J, V11, P363
[5]   Effects of mandibular advancement device for obstructive sleep apnea on temporomandibular disorders: A systematic review and meta-analysis [J].
Alessandri-Bonetti, Anna ;
Bortolotti, Francesco ;
Moreno-Hay, Isabel ;
Michelotti, Ambra ;
Cordaro, Massimo ;
Alessandri-Bonetti, Giulio ;
Okeson, Jeffrey P. .
SLEEP MEDICINE REVIEWS, 2019, 48
[6]   Diagnostic accuracy of the Berlin questionnaire and the NoSAS score in detecting risk for obstructive sleep apnea in rotating shift workers [J].
Alves de Menezes Junior, Luiz Antonio ;
Fajardo, Virginia Capistrano ;
do Nascimento Neto, Raimundo Marques ;
de Freitas, Silvia Nascimento ;
Pereira de Oliveira, Fernando Luiz ;
Pedrosa Pimenta, Fausto Aloisio ;
Lins Machado-Coelho, George Luiz ;
Meireles, Adriana Lucia .
SLEEP AND BREATHING, 2022, 26 (02) :743-751
[7]  
Ameer Batcha Wahida Ameer Batcha Wahida, 2013, Health, V5, P80
[8]   Natural history of snoring and obstructive sleep apnea in Thai school-age children [J].
Anuntaseree, W ;
Kuasirikul, S ;
Suntornlohanakul, S .
PEDIATRIC PULMONOLOGY, 2005, 39 (05) :415-420
[9]   Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea [J].
Arora, Subodh K. ;
Powell, Tyler A. ;
Foster, Shannon N. ;
Hansen, Shana L. ;
Morris, Michael J. .
SLEEP AND BREATHING, 2023, 27 (01) :137-144
[10]  
Arrazola-Cortés E, 2017, NEUROENDOCRINOL LETT, V38, P449