In-silico identification and ex-vivo validation in humans of distinct oncogenic potential of aldo-keto reductase AKR1B10 in hepatocellular carcinoma from alcohol induced liver injury

被引：0

作者：

Waters, Michael ^{[1
]}

Sukriti, Sukriti ^{[2
]}

Sharma, Chhagan ^{[3
]}

Negi, Preeti ^{[2
]}

Patel, Bhaumik ^{[4
,5
]}

Fuchs, Michael ^{[4
,6
]}

Sarin, Shiv Kumar ^{[7
]}

Puri, Puneet ^{[4
,8
]}

机构：

[1] Washington Univ, Dept Radiat Oncol, Sch Med St Louis, St Louis, MO USA

[2] Inst Liver & Biliary Sci, Dept Mol & Cellular Med, New Delhi, India

[3] Inst Liver & Biliary Sci, Dept Pathol, New Delhi, India

[4] Virginia Commonwealth Univ, Richmond, VA USA

[5] Richmond VA Med Ctr, Dept Internal Med, Sect Med Oncol, Richmond, VA USA

[6] Richmond VA Med Ctr, Sect Gastroenterol Hepatol & Nutr, Dept Internal Med, Richmond, VA USA

[7] Inst Liver & Biliary Sci, Dept Hepatol, New Delhi, India

[8] Richmond VA Med Ctr, Sect Gastroenterol Hepatol & Nutr, Richmond, VA USA

来源：

JOURNAL OF HEPATOLOGY | 2023年 / 78卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

FRI-411

引用

页码：S149 / S150

页数：2

共 17 条

[1] Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma
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[2] Serum Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) as a Potential Biomarker for Diagnosis of Hepatocellular Carcinoma
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[3] Aldo-keto reductase family 1B10 (AKR1B10): Novel biomarker and molecular target of hepatocellular carcinoma
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CANCER RESEARCH, 2012, 72
[4] Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10
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[5] Identification and characterization of functional antioxidant response elements in the promoter of the aldo-keto reductase AKR1B10 gene
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CHEMICO-BIOLOGICAL INTERACTIONS, 2017, 276 : 160 - 166
[6] Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) overexpression in tumors predicts worse overall survival in hepatocellular carcinoma
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[7] Aldo-keto reductase family 1B10 (AKR1B10) knockdown or inhibition suppresses pancreatic tumorigenesis in vitro and in vivo
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CANCER RESEARCH, 2013, 73 (08)
[8] Immunohistochemistry Detects Increased Expression of Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) in Early-Stage Hepatocellular Carcinoma
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An, Ziying
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[9] Identification of Aldo-Keto Reductase AKR1B10 as a Selective Target for Modification and Inhibition by Prostaglandin A1: Implications for Antitumoral Activity
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[10] Proteomic identification of aldo-keto reductase AKR1B10 induction after treatment of colorectal cancer cells with the proteasome inhibitor bortezomib
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Mueller, Doris
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Auer, Thomas
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MOLECULAR CANCER THERAPEUTICS, 2009, 8 (07) : 1995 - 2006

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